Results 71 to 80 of about 87,513 (276)

Intestinal gene expression in pigs: effects of reduced feed intake during weaning and potential impact of dietary components [PDF]

, 2011
The weaning transition is characterised by morphological, histological and microbial changes, often leading to weaning-associated disorders. These intestinal changes can partly be ascribed to the lack of luminal nutrition arising from the reduced feed ...
Bauer, E., Metzler-Zebeli, B.U., Mosenthin, R., Verstegen, M.W.A.   +3 more
core   +1 more source

Optimizing Pichia Pastoris Cell‐Free Protein Synthesis to Improve Economics

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Cell‐free protein synthesis (CFPS) is a powerful and versatile platform that supports a wide range of applications, from fundamental studies of the genetic code to scalable and rapid protein production. The recently developed Pichia pastoris CFPS combines advantages of both prokaryotic and eukaryotic systems, including a rapid growth rate ...
Rui Wu, Igor Koop, Gavin Murugan, Thagshanen Thillairajah, Karen M. Polizzi   +4 more
wiley   +1 more source

Microplastics and nanoplastics in water: Improving removal in wastewater treatment plants with alternative coagulants

The Canadian Journal of Chemical Engineering, EarlyView.
The contaminant removal performance of a conventional coagulant, alum, and alternative coagulants, aluminium chlorohydrate (ACH) and ACH + pDADMC, are compared in challenging wastewater treatment conditions (pH >7.8). The interactions of each coagulant with a negatively charged surface are depicted based on quartz crystal microbalance with dissipation ...
Sinan Abi Farraj, Mathieu Lapointe, Rafael S. Kurusu, Nathalie Tufenkji   +3 more
wiley   +1 more source

Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases

Frontiers in Nutrition, 2019
The polyamines putrescine, spermidine, and spermine are widely distributed polycationic compounds essential for cellular functions. Intracellular polyamine pools are tightly regulated by a complex regulatory mechanism involving de novo biosynthesis ...
Bruno Ramos-Molina, Bruno Ramos-Molina, Maria Isabel Queipo-Ortuño, Maria Isabel Queipo-Ortuño, Ana Lambertos, Ana Lambertos, Francisco J. Tinahones, Francisco J. Tinahones, Rafael Peñafiel, Rafael Peñafiel   +9 more
doaj   +1 more source

Abnormal flowers and pattern formation in floral [PDF]

, 1989
“From our acquaintance with this abnormal enabled to unveil the secrets that normal us, and to see distinctly what, from the regular we can only infer.” - J. W.
Bowman, John L., Meyerowitz, Elliot M., Smyth, David R.   +2 more
core  

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Calcium-Sensing Receptor as a Novel Target for the Treatment of Idiopathic Pulmonary Fibrosis

Biomolecules
Idiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and no curative therapies. Fibroblast activation by transforming growth factor β1 (TGFβ1) and disrupted metabolic pathways, including the arginine–polyamine pathway, play crucial ...
Kasope Wolffs, Renjiao Li, Bethan Mansfield, Daniel A. Pass, Richard T. Bruce, Ping Huang, Rachel Paes de Araújo, Bahareh Sadat Haddadi, Luis A. J. Mur, Jordanna Dally, Ryan Moseley, Rupert Ecker, Harry Karmouty-Quintana, Keir E. Lewis, A. John Simpson, Jeremy P. T. Ward, Christopher J. Corrigan, Renata Z. Jurkowska, Benjamin D. Hope-Gill, Daniela Riccardi, Polina L. Yarova   +20 more
doaj   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. [PDF]

, 2016
There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased ...
Black, Stephen M, Desai, Ankit A, Fineman, Jeffrey R, Garcia, Joe GN, Kinchen, Jason M, Maltepe, Emin, Meadows, Mary L, Mohney, Robert P, Rafikov, Ruslan, Rafikova, Olga, Yuan, Jason X-J   +10 more
core   +3 more sources

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source