Results 61 to 70 of about 65,399 (230)
Difluoromethylornithine (DFMO) and AMXT 1501 inhibit capsule biosynthesis in pneumococci
Scientific Reports, 2022 Polyamines are small cationic molecules that have been linked to various cellular processes including replication, translation, stress response and recently, capsule regulation in Streptococcus pneumoniae (Spn, pneumococcus).
Moses B. Ayoola +7 more
doaj +1 more source
Animal Research and One Health, EarlyView.Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang +6 more
wiley +1 more source
Dietary and Gut Microbiota Polyamines in Obesity- and Age-Related Diseases
Frontiers in Nutrition, 2019 The polyamines putrescine, spermidine, and spermine are widely distributed polycationic compounds essential for cellular functions. Intracellular polyamine pools are tightly regulated by a complex regulatory mechanism involving de novo biosynthesis ...
Bruno Ramos-Molina +9 more
doaj +1 more source
Basal condition of polyamine concentrations.
, 2013 Basal condition of polyamine concentrations.
Xu Gu (276054) +3 more
core +1 more source
Animal Research and One Health, EarlyView.Multifunctional roles of functional amino acids in regulating meat quality in ruminants: Functional amino acids (FAAs) regulate ruminant meat quality through multiple interconnected mechanisms, including antioxidant protection, metabolic regulation, signal transduction, structural support, and gene expression modulation.
Zixin Liu +5 more
wiley +1 more source
The effects of polyamine ftx-3.3 and polyamine amide sftx-3.3 on acetyccholine release
, 1995 This article discusses the effects of polyamine ftx-3.3 and polyamine amide sftx-3.3 on acetyccholine ...
Moya, E. +4 more
core +2 more sources
Ribavirin Induces Polyamine Depletion via Nucleotide Depletion to Limit Virus Replication
Cell Reports, 2019 Summary: Common antivirals include nucleoside or nucleotide analogs with base prodrugs. The antiviral ribavirin, a US Food and Drug Administration (FDA)-approved nucleoside antimetabolite, halts guanine production, mutagenizes viral genomes, and ...
Patrick M. Tate +2 more
doaj +1 more source
BMEMat, EarlyView.The challenges of bioprosthetic heart valves (BHV) with respect to calcification, infection, and poor durability are tackled by surface engineering of hyperbranched poly‐L‐lysine (HBPL), providing a translational solution to improve long‐term valve performance.
Pai Peng +7 more
wiley +1 more source
Calcium-Sensing Receptor as a Novel Target for the Treatment of Idiopathic Pulmonary Fibrosis
BiomoleculesIdiopathic pulmonary fibrosis (IPF) is a disease with a poor prognosis and no curative therapies. Fibroblast activation by transforming growth factor β1 (TGFβ1) and disrupted metabolic pathways, including the arginine–polyamine pathway, play crucial ...
Kasope Wolffs +20 more
doaj +1 more source
Coxsackievirus B3 Responds to Polyamine Depletion via Enhancement of 2A and 3C Protease Activity
Viruses, 2019 Polyamines are small positively-charged molecules abundant in eukaryotic cells that are crucial to RNA virus replication. In eukaryotic cells, polyamines facilitate processes such as transcription, translation, and DNA replication, and viruses similarly ...
Courtney N. Dial +3 more
doaj +1 more source