Results 41 to 50 of about 65,399 (230)
Polyamine Metabolism in Disease and Polyamine-Targeted Therapies [PDF]
, 2019 Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis ...
Murray-Stewart, Tracy
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Regulation of ornithine decarboxylase expression
, 2006 It has become increasingly obvious during the last two decades that a multitude of cellular processes are highly dependent on adequate levels of polyamines (1–6).
Persson, Lo,, Lund University.
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A Cyclodextrin Hydrogel For Polyamine Capturing In Periodontitis Treatment
International Dental JournalAim or purpose: Polyamine accumulation exacerbates inflammation and tissue destruction in periodontitis, but its therapeutic potential remains unclear, and this study evaluates a polyamine-scavenging hydrogel for periodontitis inflammation by restoring ...
Simeng Wang, Jianhua Li, Weiwei Zhao
doaj +1 more source
, 2011 Polyamines are ubiquitous molecules that are involved in a number of important cellular processes. Aberrations in their function or metabolism play a role in diseases such as cancer and parasitic infection.
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Advanced Science, EarlyView.Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen +10 more
wiley +1 more source
Food & Nutrition Research, 2011 Background: Dietary polyamines have been shown to give a significant contribution to the body pool of polyamines. Knowing the levels of polyamines (putrescine, spermidine, and spermine) in different foods and the contribution of daily food choice to ...
Mohamed Atiya Ali +3 more
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Advanced Science, EarlyView.Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang +12 more
wiley +1 more source
Opposing Roles for ATP13A2 and ATP13A3 in Breast Cancer Subtype-Specific Polyamine Homeostasis
BiomoleculesPolyamine homeostasis is essential for normal cellular function and is maintained through coordinated regulation of polyamine biosynthesis, catabolism, and transport.
Emily Meeus +3 more
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Modulation of polyamine catabolism in pea seedlings by calcium during salinity stress
Plant Protection Science, 2012 The relation of polyamine catabolism in the response of Pisum sativum to salinity stress was investigated. Pea seedlings were grown in increasing concentrations of Na+ or K+ or at different concentration ratios of these ions. We studied the effect of Ca2+
Jana Piterková +4 more
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Spermine-NBD as Fluorescent Probe for Studies of Polyamine Transport System in Leishmania Donovani [PDF]
, 2018 This study describes the synthesis of fluorescent probes as potential substrates for the polyamine transport system (PTS) of Leishmania donovani. A competitive radioassay was used to determine the most efficient probe.
Jean-Christophe, Cintrat +5 more
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