Results 41 to 50 of about 58,354 (282)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Regulation of ornithine decarboxylase expression [PDF]
, 2006 It has become increasingly obvious during the last two decades that a multitude of cellular processes are highly dependent on adequate levels of polyamines (1–6).
Persson, Lo,, Lund University.
core +1 more source
Practical Synthesis of Polyamine Succinamides and Branched Polyamines
ChemistryOpen, 2022 AbstractAntibiotic resistance is now a growing threat to human health, further exacerbated by the lack of new antibiotics. We describe the practical synthesis of a series of substituted polyamine succinamides and branched polyamines that are potential new antibiotics against both Gram‐positive and Gram‐negative bacteria, including MRSA and Pseudomonas ...
Abdulaziz H. Alkhzem +3 more
openaire +4 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Spermine-NBD as Fluorescent Probe for Studies of Polyamine Transport System in Leishmania Donovani [PDF]
, 2018 This study describes the synthesis of fluorescent probes as potential substrates for the polyamine transport system (PTS) of Leishmania donovani. A competitive radioassay was used to determine the most efficient probe.
Jean-Christophe, Cintrat +5 more
core +1 more source
Biology, 2023 Research suggests that androgens increase skeletal muscle growth by modulating polyamine biosynthesis. As such, the objective of this study was to investigate effects of anabolic hormones, polyamine precursors, and polyamines relative to proliferation ...
Laura A. Motsinger +8 more
doaj +1 more source
Molecular Adsorbing Host•Guest (MAHG) Crystals: A New Paradigm for Porous Materials?
Advanced Functional Materials, EarlyView.Networking! Introduction of guest molecules in macrocycles before crystallization profoundly influences the material obtained in terms of structure and function. Beside simplicity and porous space improvement, this approach is endowed with a huge potential given the myriad of potential guest molecules that can be used to tune this burgeoning class of ...
Ingrid Suzana +4 more
wiley +1 more source
Polyamine Metabolism in Disease and Polyamine-Targeted Therapies [PDF]
, 2019 Polyamines are ubiquitous polycations essential for all cellular life. The most common polyamines in eukaryotes, spermine, spermidine, and putrescine, exist in millimolar intracellular concentrations that are tightly regulated through biosynthesis ...
Murray-Stewart, Tracy
core +1 more source
Antizyme Inhibitors in Polyamine Metabolism and Beyond: Physiopathological Implications
Medical Sciences, 2018 The intracellular levels of polyamines, cationic molecules involved in a myriad of cellular functions ranging from cellular growth, differentiation and apoptosis, is precisely regulated by antizymes and antizyme inhibitors via the modulation of the ...
Bruno Ramos-Molina +2 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan +10 more
wiley +1 more source