Results 21 to 30 of about 29,329 (143)

Polygonum multiflorum Stilbene Glycoside Oligomers induce the ferroptosis of triple negative breast cancer cells [PDF]

BMC Cancer
The quality control testing component and main active ingredient of Polygonum multiflorum Thunb. (P. multiflorum), known as trans-2,3,5,4ʹ-tetrahydroxystilbene 2-O-β-D-glucopyranoside (TSG), exhibits diverse biological activities.
Xiaomeng Lin, Hua Yang, Tingting Cai, Zhangshuo Yang, Siyun Niu, Hui Jia   +5 more
doaj   +2 more sources

Polygonumnolides A1-B3, minor dianthrone derivatives from the roots of Polygonum multiflorum Thunb. [PDF]

Arch Pharm Res, 2018
Seven new dianthrone glycosides, named polygonumnolides A1–B3 (1–7), were isolated from the 70 % EtOH extract of the dried roots of Polygonum multiflorum Thunb. using column chromatography and preparative high-performance liquid chromatography.
Yang J, Yan Z, Ren J, Dai Z, Ma S, Wang A, Su Y.   +6 more
europepmc   +2 more sources

Discovery of anthraquinones as potent Notum inhibitors for treating osteoporosis by integrating biochemical, phytochemical, computational, and experimental assays [PDF]

Journal of Pharmaceutical Analysis
Osteoporosis, a severe systemic skeletal disorder characterized by decreased bone mineral density, leads to increased risks of bone fragility and fracture.
Jia Guo, Yuqing Song, Mengru Sun, Jun Qian, Dihang See, Tian Tian, Yunqing Song, Wei Liu, Hongping Deng, Yao Sun, Guangbo Ge, Yongfang Zhao   +11 more
doaj   +2 more sources

Comprehensive Evaluation of Toxicological Profile and Immunomodulatory Impact of an Immune Enhancing Oral Liquid [PDF]

Foods
Traditional Chinese herbal medicines are characterized by multi-component synergy and have garnered significant attention in the healthcare research. The Immune Enhancing Oral Liquid, formulated with Polygonum multiflorum Thunb.
Hongzhang Chen, Zhuming Ye, Sihe Chen, Wenquan Huang, Ying Lin, Qixin Kan   +5 more
doaj   +2 more sources

UPLC/MS/MS-Based Metabolomics Study of the Hepatotoxicity and Nephrotoxicity in Rats Induced by Polygonum multiflorum Thunb. [PDF]

ACS Omega, 2020
Yan Yan, Ning Shi, Xuyang Han, Guodong Li, Binyu Wen, Jian Gao   +5 more
doaj   +2 more sources

2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG) from <i>Polygonum multiflorum</i> Thunb.: A Systematic Review on Anti-Aging. [PDF]

Int J Mol Sci
The global rise in aging populations has made healthy longevity a critical priority in medical research. 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG), the primary bioactive component of Polygonum multiflorum Thunb.
Zhu C, Li J, Tang W, Li Y, Lin C, Peng D, Yang C.   +6 more
europepmc   +2 more sources

The Root of Polygonum multiflorum Thunb. Alleviates Non-Alcoholic Steatosis and Insulin Resistance in High Fat Diet-Fed Mice. [PDF]

Nutrients, 2020
Non-alcoholic steatosis and insulin resistance are critical health problems and cause metabolic complications worldwide. In this study, we investigated the molecular mechanism of Polygonum multiflorum Thunb.
Jung S, Son H, Hwang CE, Cho KM, Park SW, Kim H, Kim HJ.   +6 more
europepmc   +2 more sources

A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside

Frontiers in Pharmacology, 2022
Polygonum multiflorum Thunb. (He-shou-wu in Chinese), a Chinese botanical drug with a long history, is widely used to treat a variety of chronic diseases in clinic, and has been given the reputation of “rejuvenating and prolonging life” in many places. 2,
Cheng Wang, Shu Dai, Lihong Gong, Ke Fu, Cheng Ma, Yanfang Liu, Honglin Zhou, Yunxia Li   +7 more
doaj   +1 more source

Polygonum multiflorum Thunb. Hot Water Extract Reverses High-Fat Diet-Induced Lipid Metabolism of White and Brown Adipose Tissues in Obese Mice. [PDF]

Plants (Basel), 2021
The purpose of the present study was to determine whether an anti-obesity effect of a Polygonum multiflorum Thunb. hot water extract (PW) was involved in the lipid metabolism of white adipose tissue (WAT) and brown adipose tissue (BAT) in high-fat diet ...
Choi RY, Lee MK.
europepmc   +2 more sources

Herb-Induced Liver Injury Related to Reynoutria multiflora (Thunb.) Moldenke: Risk Factors, Molecular and Mechanistic Specifics

Frontiers in Pharmacology, 2021
Herbal medicine is widely used in Asia as well as the west. Hepatotoxicity is one of the most severe side effects of herbal medicine which is an increasing concern around the world.
Xing-Ran Zhai, Zheng-Sheng Zou, Zheng-Sheng Zou, Zheng-Sheng Zou, Jia-Bo Wang, Jia-Bo Wang, Xiao-He Xiao, Xiao-He Xiao   +7 more
doaj   +1 more source