Results 31 to 40 of about 29,329 (143)

Miquelianin, a main functional flavonoid of lotus leaf, induces thermogenic signature via p38‐PINK1‐PARKIN‐mediated mitophagy and mimicking NRF2 signaling during brown adipocyte differentiation

open access: yesFood Frontiers, Volume 4, Issue 4, Page 1831-1844, December 2023., 2023
Extract of lotus leaf exerts the strongest thermogenesis among 12 ingredients in C3H10T1/2 cells. Miquelianin induces brown and beige signatures in C3H10T1/2 cells. Miquelianin retains thermogenic capacity through p38‐PINK1‐PRKN‐mediated mitophagy and mimicking NRF2 signaling.
Zhenyu Wang   +7 more
wiley   +1 more source

Diagnosis and Management of Drug-Induced Liver Injury After the Use of Polygonum multiflorum [PDF]

open access: yes, 2022
Polygonum multiflorum, a species of flowering plant in the buckwheat family, is widely used in alternative medicine. However, a growing body of literature has implicated P. multiflorum as a cause of drug-induced liver injury.
Gill, Ryan M.   +4 more
core   +1 more source

Extracellular matrix turnover: phytochemicals target and modulate the dual role of matrix metalloproteinases (MMPs) in liver fibrosis

open access: yesPhytotherapy Research, Volume 37, Issue 11, Page 4932-4962, November 2023., 2023
Phytochemicals treat liver fibrosis in chemicals induced in‐vivo and in‐vitro liver fibrosis models. MMPs are potential drug targets by novel natural drugs for treating hepatic fibrosis. MMPs regulate ECM turnover, fibrolysis, and stellate cell activation through alternative mechanisms.
Usman Sabir   +2 more
wiley   +1 more source

Characterization of Antioxidant Constituents and Geographical Differentiation of <i>Polygonum multiflorum</i> Thunb. Leaves Using 2D-LC-ECD and UHPLC-Orbitrap-MS/MS. [PDF]

open access: yesAntioxidants (Basel)
This study established an activity-oriented analysis method based on offline two-dimensional liquid chromatography–electrochemical detection (2D-LC-ECD) combined with ultra-high-performance liquid chromatography–Orbitrap-MS/MS (UHPLC-Orbitrap-MS/MS ...
Tan Z   +9 more
europepmc   +2 more sources

Relationship among Chinese herb polysaccharide (CHP), gut microbiota, and chronic diarrhea and impact of CHP on chronic diarrhea

open access: yesFood Science &Nutrition, Volume 11, Issue 10, Page 5837-5855, October 2023., 2023
This review systematically summarizes the relationship among intestinal flora, chronic diarrhea, and polysaccharides as well as recent progress on the impacts of Chinese herb polysaccharides on the gut microbiota and recent advances on the possible role of CHP in chronic diarrhea.
Hong Xue   +3 more
wiley   +1 more source

Stilbene‐based derivatives as potential inhibitors of trimethylamine (TMA)‐lyase affect gut microbiota in coronary heart disease

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 93-100, January 2023., 2023
Docking results showed Resveratroloside had the highest Vina score, indicating that it was the most active and might be employed as a lead molecule for further structural modification. The possible action process of TMA‐Lyase lead compound was described, which further affects the occurrence and development of CHD.
Jincai Li   +3 more
wiley   +1 more source

Gastrodia elata BI.:A Comprehensive Review of Its Traditional Use, Botany, Phytochemistry, Pharmacology, and Pharmacokinetics

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Ethnopharmacological Relevance. The medicinal use of Gastrodia elata BI., a dry tuber of the orchid family, has a long history. Gastrodia elata BI. has the functions of calming the liver, relieving muscle spasms, and dispelling gas. Aim of this Review.
Ya-Nan Wu   +8 more
wiley   +1 more source

Reduction of Atherosclerosis in Cholesterol-Fed Rabbits and Decrease of Expressions of Intracellular Adhesion Molecule-1 and Vascular Endothelial Growth Factor in Foam Cells by a Water-Soluble Fraction of Polygonum multiflorum

open access: yesJournal of Pharmacological Sciences, 2005
Polygonum multiflorum stilbeneglycoside (PMS) is a water-soluble fraction of Polygonum multiflorum Thunb., one of the most famous tonic traditional Chinese medicines, that has protective effects on the cardiovascular system.
Peng-Yuan Yang   +8 more
doaj   +1 more source

Exploring the combination and modular characteristics of herbs for alopecia treatment in traditional Chinese medicine: an association rule mining and network analysis study

open access: yesBMC Complementary and Alternative Medicine, 2018
Background Although alopecia affects the quality of life, its pathogenesis is unknown, because cellular interactions in the hair follicle are complex. Several authors have suggested using herbal medicine to treat alopecia, and bioinformatics and network ...
Jungtae Leem   +4 more
doaj   +1 more source

Protective effect of tetrahydroxystilbene glucoside on 6-OHDA-induced apoptosis in PC12 cells through the ROS-NO pathway. [PDF]

open access: yesPLoS ONE, 2011
Oxidative stress plays an important role in the pathogenesis of neurodegenerative diseases, such as Parkinson's disease. The molecule, 2,3,5,4'-tetrahydr- oxystilbene-2-O-β-D-glucoside (TSG), is a potent antioxidant derived from the Chinese herb ...
Lizhen Tao   +9 more
doaj   +1 more source

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