Results 41 to 50 of about 609 (153)

Disposable electrocatalytic sensor for whole blood NADH monitoring

open access: yesScientific Reports, 2022
Monitoring nicotinamide adenine dinucleotide (NADH) is important because NADH is involved in cellular redox reactions and cellular energy production. Currently, few biosensors quantify NADH in whole blood.
JuKyung Lee   +6 more
doaj   +1 more source

Intratracheal exposure to polyhexamethylene guanidine phosphate disrupts coordinate regulation of FXR-SHP-mediated cholesterol and bile acid homeostasis in mouse liver

open access: yesEcotoxicology and Environmental Safety, 2022
A public health crisis in the form of a significant incidence of fatal pulmonary disease caused by repeated use of humidifier disinfectants containing polyhexamethylene guanidine phosphate (PHMG) recently arose in Korea.
You-Jin Choi   +10 more
doaj   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

open access: yes, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile   +41 more
core   +3 more sources

p53: A Key Protein That Regulates Pulmonary Fibrosis

open access: yesOxidative Medicine and Cellular Longevity, Volume 2020, Issue 1, 2020., 2020
Pulmonary fibrosis is a progressively aggravating lethal disease that is a serious public health concern. Although the incidence of this disease is increasing, there is a lack of effective therapies. In recent years, the pathogenesis of pulmonary fibrosis has become a research hotspot.
Qi Wu   +8 more
wiley   +1 more source

Humidifier disinfectant lung injury, how do we approach the issues? [PDF]

open access: yesEnvironmental Health and Toxicology, 2016
A large portion of the Korean population has been exposed to toxic humidifier disinfectants (HDs), and considering that the majority of the victims are infants, the magnitude of the damage is expected to be considerably larger than what has currently ...
Jihyun Emma Choi   +7 more
doaj   +1 more source

Effect of polymeric biocide polyhexamethylene guanidine hydrochloride on morpho-physiological and biochemical parameters of wheat seedlings under copper stress [PDF]

open access: yes, 2020
Aim. To study the effect of polymeric biocide polyhexamethylene guanidine hydrochloride (PHMG-Cl) on morphophysiological and biochemical parameters of wheat seedlings in the presence of toxic concentration of copper ions. Methods.
L. Lyoshyna   +5 more
core   +2 more sources

Non-Destructive Monitoring via Electrochemical NADH Detection in Murine Cells

open access: yesBiosensors, 2022
Nicotinamide adenine dinucleotide (NADH) is an important cofactor involved in metabolic redox reactions in living cells. The detection of NADH in living animal cells is a challenge.
Ju Kyung Lee   +6 more
doaj   +1 more source

In vitro assessment of skin sensitization, irritability and toxicity of bacteriocins and reuterin for possible topical applications [PDF]

open access: yes, 2022
Bacteriocins and reuterin are promising antimicrobials for application in food, veterinary, and medical sectors. In the light of their high potential for application in hand sanitizer, we investigated the skin toxicity of reuterin, microcin J25, pediocin
Biron, Éric   +5 more
core   +1 more source

The activity of PHMB and other guanidino containing compounds against acanthamoeba and other ocular pathogens [PDF]

open access: yes, 2022
© 2022 The Authors. Published by MDPI. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3390/microorganisms10071375In ...
Al Ani, Enas   +3 more
core   +2 more sources

The resistance of the yeast Saccharomyces cerevisiae to the biocide polyhexamethylene biguanide: involvement of cell wall integrity pathway and emerging role for YAP1 [PDF]

open access: yes, 2011
Background Polyhexamethylene biguanide (PHMB) is an antiseptic polymer that is mainly used for cleaning hospitals and pools and combating Acantamoeba infection.
Carolina Elsztein   +2 more
core   +1 more source

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