Results 11 to 20 of about 729 (148)
Structure-Function Analysis of Enzymes of the Polyisoprenyl-Phosphate Hexose-1-Phosphate Transferase family [PDF]
, 2011 Enzymes of the polyisoprenyl-phosphate hexose-1-phosphate transferase (PHPT) family are integral membrane proteins that initiate the synthesis of glycans by catalyzing the transfer of a hexose-1-phosphate sugar from UDP-hexose to the lipid carrier undecaprenyl phosphate (Und-P).
Kinnari B. Patel
openalex +2 more sources
Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer’s Disease [PDF]
Oxidative Medicine and Cellular Longevity, Volume 2016, Issue 1, 2016., 2016 This review is focused on the possible causes of mitochondrial dysfunction in AD, underlying molecular mechanisms of this malfunction, possible causes and known consequences of APP, Aβ, and hyperphosphorylated tau presence in mitochondria, and the contribution of altered lipid metabolism (nonsterol isoprenoids) to pathological processes leading to ...
Beata Pająk +3 more
wiley +4 more sources
Determination of the anomeric configuration of glycosyl esters of nucleoside pyrophosphates and polyisoprenyl phosphates by fast-atom bombardment tandem mass spectrometry [PDF]
Journal of the American Society for Mass Spectrometry, 1996 Collision-induced dissociation of the deprotonated molecules of glycosyl esters of nucleoside pyrophosphates and polyisoprenyl (dolichyl and polyprenyl) phosphates results in distinct fragmentation patterns that depend on cis-trans configuration of the phosphodiester and 2″ (or 2', respectively)-hydroxyl groups of the glycosyl residue. At the collision-
Beata A. Wolucka +3 more
openalex +3 more sources
Purification and Characterization of a Polyisoprenyl Phosphate Phosphatase from Pig Brain [PDF]
Journal of Biological Chemistry, 1998 David W. Frank, Charles J. Waechter
openalex +3 more sources
Structure-Function Analysis of UDP-Sugar: Polyisoprenyl Phosphate Sugar-1-Phosphate Transferases [PDF]
, 2013 The synthesis of lipid-linked glycans is a conserved process in eukaryotes and prokaryotes that is initiated by two major enzyme families: the polyisoprenyl-phosphate hexose-1-phosphate transferases (PHPTs) and the polyisoprenyl-phosphate N-acetylaminosugar-1-phosphate transferases (PNPTs). These enzymes contain multiple membrane domains and transfer a
Sarah E. Furlong
openalex +1 more source
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016 Chris Whitfield
openalex +3 more sources
iScience, 2022 Summary: Lipid phosphate phosphatases are a family of enzymes with diverse cellular metabolic functions. Phospholipid phosphatase 6 (PLPP6) is a regulator of cellular polyisoprenyl phosphates; however, its in vivo functions remain to be determined. Here,
Thayse R. Brüggemann +11 more
doaj +1 more source
Molecular Microbiology, Volume 120, Issue 3, Page 408-424, September 2023., 2023 In Enterococcus faecalis, CroRS regulates the expression of cell envelope biosynthesis pathways to maintain homeostasis and confer tolerance upon antimicrobial challenge. Loss of function mutations in the respiratory branch of the isoprenoid pathway appears to rescue tolerance in a croRS deletion mutant.
Francesca O. Todd Rose +7 more
wiley +1 more source
New Phytologist, Volume 239, Issue 3, Page 1098-1111, August 2023., 2023 Summary Lettuce produces natural rubber (NR) with an average Mw of > 1 million Da in laticifers, similar to NR from rubber trees. As lettuce is an annual, self‐pollinating, and easily transformable plant, it is an excellent model for molecular genetic studies of NR biosynthesis.
Moonhyuk Kwon +8 more
wiley +1 more source
ChemMedChem, Volume 16, Issue 24, Page 3730-3738, December 14, 2021., 2021 Precision nanomedicines can improve osteosarcoma treatments by enhancing the action of cytostatic agents through selective targeting to the bone tumor area. HbisP−Sq, a lipid molecule with high affinity for calcium ions present in HA has been successfully synthetized.
Carlos Rodríguez‐Nogales +4 more
wiley +1 more source