Structurally diverse secondary metabolites from the dung-inhabiting fungus Botryotrichum murorum. [PDF]
Charria-Girón E +3 more
europepmc +1 more source
Global profiling of polyketide synthases in facultative multicellular eukaryotes. [PDF]
Günther M +5 more
europepmc +1 more source
Evolutionary Reprogramming of Acyltransferase Domains in Polyene Macrolide Pathways. [PDF]
Zhang L +5 more
europepmc +1 more source
The terrein biosynthetic gene cluster of Aspergillus terreus: structure, function, regulation, and similar gene clusters. [PDF]
Németh MZ, Csíkos S, Kovács GM.
europepmc +1 more source
The Biosynthetic Gene Cluster of Boydines in Scedosporium apiospermum. [PDF]
Carvalho C +5 more
europepmc +1 more source
Polyketide synthase-like functionality acquired by plant fatty acid elongase. [PDF]
Kim H +10 more
europepmc +1 more source
β-Branching in the biosynthesis of bongkrekic acid: a complex affair. [PDF]
Hiseman MEM +8 more
europepmc +1 more source
The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases [PDF]
Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis. In modular PKSs, the polyketide chain is assembled by the successive condensation of activated carboxylic acid-derived units, where chain extension occurs with ...
David H Kwan, Frank Schulz
exaly +8 more sources
Structural control of polyketide formation in plant-specific polyketide synthases [PDF]
Polyketide synthases (PKSs) generate molecular diversity by utilizing different starter molecules and by controlling the final length of the polyketide. Although exploitation of this mechanistic variability has produced novel polyketides, the structural foundation of this versatility is unclear. Plant-specific PKSs are essential for the biosynthesis of
Joseph M Jez +2 more
exaly +5 more sources

