Results 131 to 140 of about 27,304 (237)

Polyketides with Cardioprotective Bioactivities from Sponge-Associated Fungus Aspergillus giganteus MA46-5

Molecules
One pair of novel enantiomers, gigantdioxin A (+)-1 and B (−)-1, with a skeleton of benzo[d][1,3]dioxin; a new acetophenone gigantone A (3); a known 3-chlorogentisyl alcohol (2), which is the bioprecursor of 1; acetophenone (4); and chromone derivative ...
Ying-Tong Lin, Xiao-Wei Yao, Zheng-Wu Luo, Wei-Xin Jiang, Yin-Fei Wu, Ze-Jun Li, Xue-Wei Duan, Meng-Dan Zhang, Yuan-Yuan Cheng, Cui-Xian Zhang   +9 more
doaj   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. ABSTRACT Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Reduzierte Polyketide

, 2012
Polyketide sind eine strukturell heterogene Gruppe von Naturstoffen mit oftmals faszinierenden Bioaktivitäten die therapeutisch genutzt werden können. Die für den Einsatz in der Medizin meist notwendige Derivatisierung dieser Substanzen stellt große Herausforderungen an die modernen chemischen Wissenschaften.
openaire   +2 more sources

Insights from meta‐analysis for efficient docosahexaenoic acid production in thraustochytrids through advanced cultivation and fermentation strategies

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 1041-1060, March/April 2026.
Abstract This systematic review examines strategies for docosahexaenoic acid (DHA) production by thraustochytrids, focusing on cultivation techniques, fermentation technologies, and carbon/nitrogen optimization to increase productivity. Among 169 eligible articles, the 100 most productive studies (0.7–10.3 g DHA L−1 per day) were analyzed. Quantitative
Jhiovana Cristielly Carrera Silva da Costa, Lucas Araújo Guimarães, Andre da Luz de Freitas, Luciana Porto de Souza Vandenberghe, Gilberto Vinícius de Melo Pereira, Carlos Ricardo Soccol, Hervé Louis Ghislain Rogez   +6 more
wiley   +1 more source

Raw citrus by‐product valorization: unlocking the potential of biotransformation by Talaromyces amestolkiae to obtain cellulolytic enzymes and natural colorants

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 806-816, March/April 2026.
Abstract Agro‐industrial by‐products can be used as valuable nutrient sources for the sustainable production of high‐value‐added compounds. The goal of this study was utilize raw citrus industrial by‐product (RCB) as a carbon source for the simultaneous production of red colorants and enzymes by the filamentous fungus Talaromyces amestolkiae under lab ...
Caio de Azevedo Lima, Heitor B. S. Bento, Flávio Pereira Picheli, Fernanda de Oliveira, Almiro Pires da Silva Neto, Danielle Biscaro Pedrolli, Fernando Masarin, Silvio Silvério da Silva, Valéria Carvalho Santos‐Ebinuma   +8 more
wiley   +1 more source

Comparative Analysis of Fungal Communities and the Key “Golden‐Flower” Fungi in Fu Brick Tea From Seven Chinese Regions and Their Effects on the Quality of Summer‐Autumn Tea

Food Frontiers, Volume 7, Issue 2, March 2026.
This study systematically investigated 52 Fu brick tea (FBT) samples collected from seven representative regions in China. High‐through put sequencing revealed that Aspergillus, Wallemia, and Candida were the predominant fungal genera across the samples.
Lisha Ran, Jinqi Zhao, Mengyao Ma, Yiqiao Zhao, Shiyu Guo, Yu Xiao, Zhonghua Liu, Jianan Huang, Kunbo Wang, Mingzhi Zhu   +9 more
wiley   +1 more source

Cardamonin Commands the Colonic Metabolite Columbianetin Acetate to Compete Against LPS in Binding HMGB1 in the Kidney, Preventing Lipopolysaccharide‐Induced Renal Tubular Pyroptosis

Food Frontiers, Volume 7, Issue 2, March 2026.
Cardamonin upregulate sd the intestinal metabolite columbianetin acetate, which competitively bound HMGB1 to prevent LPS‐induced renal tubular cell pyroptosis (the figure is created with BioRender). ABSTRACT Sepsis‐associated acute kidney injury (SA‐AKI) results in high mortality due to the lack of effective interventions. The current study reports the
Zihui Zhou, Xuechun Sun, Jian Zhou, Huali Meng, Pengfei Fan, Yufeng Chu, Hao Wu   +6 more
wiley   +1 more source

Biosynthesis gene cluster‐containing species drive microbial community stability under thermal stress through enhanced ecological cohesion

iMetaOmics, Volume 3, Issue 1, March 2026.
The study framework for exploring microbial community assembly and community stability of biosynthesis gene cluster (BGC)‐containing species under thermal stress (20°C–65°C) during 39 days of spontaneous fermentation. Temperature gradients during spontaneous fermentation reshape microbial community assembly, driving pronounced succession in both ...
Shibo Ban, Binghao He, Yang Song, Xin Li An, Yan Xu, Qun Wu, Yu Shi   +6 more
wiley   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Dereplicative Combination of HPLC/DAD/MS and 2D NMR to Identify Lichexanthone Isomers in Lichen Extracts

Phytochemical Analysis, Volume 37, Issue 2, Page 330-343, March 2026.
ABSTRACT Introduction Lichexanthones are the major xanthones found in lichens. They present a high degree of isomerism, which makes their identification tedious. Xanthones are known to occur in lichens according to chemosyndromes, and these compounds act as chemotaxonomic markers.
Solenn Ferron, Marylène Chollet‐Krugler, Hermann Pinson, Rania Marzoug, Philippe Uriac, Françoise Lohézic‐Le Dévéhat   +5 more
wiley   +1 more source