Actinomycetes are remarkable producers of compounds essential for human and veterinary medicine as well as for agriculture. The genomes of those microorganisms possess several sets of genes (biosynthetic gene cluster (BGC)) encoding pathways for the ...
Helene L. Robertsen +1 more
doaj +1 more source
Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya
Fungi comprise the second most species-rich organism group after that of insects. Recent estimates hypothesized that the currently reported fungal species range from 3.5 to 5.1 million types worldwide. Fungi can grow in a wide range of habitats, from the
Joana D. M. de Sá +3 more
doaj +1 more source
Structure determination of a 4-pyrone from the liverwort Plagiochila bifaria (Sw.) Lindenb. (Plagiochilaceae) [PDF]
The centenary of the presentation in 1907 of the "polyketide" hypothesis by Collie, along with his use of a 4-pyrone as an example, is marked by reporting the discovery and isolation of 2-(3,4-dimethoxyphenethyl)-6-methyl-4-pyrone from <i> ...
Rycroft, D.S.
core
Polyketides, Toxins and Pigments in Penicillium marneffei [PDF]
Penicillium marneffei (synonym: Talaromyces marneffei) is the most important pathogenic thermally dimorphic fungus in China and Southeastern Asia. The HIV/AIDS pandemic, particularly in China and other Southeast Asian countries, has led to the emergence ...
Lau, SKP, Tam, EWT, Tsang, CC, Woo, PCY
core +2 more sources
A new polyketide erubescensoic acid (1), and the previously reported xanthonopyrone, SPF-3059-26 (2), were isolated from the uninvestigated fractions of the ethyl acetate crude extract of the marine sponge-associated fungus Penicillium erubescens ...
Decha Kumla +8 more
doaj +1 more source
Multifunctional polyketide synthase genes identified by genomic survey of the symbiotic dinoflagellate, Symbiodinium minutum [PDF]
Table S1. Predicted domains from transcriptome contigs Figure S1. Expression of KS domain-containing genes on scaffolds of S. minutum. Read coverages of RNAseq (gray line) on KS domain-containing genes (surrounded by green) show expression in our ...
Eiichi Shoguchi +4 more
core +4 more sources
Genome‐Guided Discovery of Antimalarial 4‐Amino‐2,4‐Pentadienoate‐Containing Cyclolipodepsipeptides
Halogenated and glycosylated 4‐amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) exhibit potent antiplasmodial activity (IC50 = 25–161 nM) against drug‐sensitive and resistant Plasmodium falciparum strains. ABSTRACT 4‐Amino‐2,4‐pentadienoate‐containing cyclolipodepsipeptides (APD‐CLDs) represent a structurally distinctive family of ...
Hartono Candra +10 more
wiley +1 more source
Comprehensive Description of Fusarium graminearum Pigments and Related Compounds
Several studies have explored in depth the biochemistry and genetics of the pigments present in Fusarium graminearum, but there is a need to discuss their relationship with the mold’s observable surface color pattern variation throughout its ...
Edgar Cambaza
doaj +1 more source
Secondary metabolism of the forest pathogen Dothistroma septosporum : a thesis presented in the partial fulfilment of the requirements for the degree of Doctor of Philosophy (PhD) in Genetics at Massey University, Manawatu, New Zealand [PDF]
Dothistroma septosporum is a fungus causing the disease Dothistroma needle blight (DNB) on more than 80 pine species in 76 countries, and causes serious economic losses. A secondary metabolite (SM) dothistromin, produced by D. septosporum, is a virulence
Ozturk, Ibrahim Kutay
core
Recent advances in expanding the coverage of the lipidome [PDF]
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core +1 more source

