Results 21 to 30 of about 3,055 (192)
Journal of the American Chemical Society, 2023 The contents of biological cells are retained within compartments formed of phospholipid membranes. The movement of material within and between cells is often mediated by the fusion of phospholipid membranes, which allows mixing of contents or excretion of material into the surrounding environment.
Stephen D. P. Fielden +4 more
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PANC-1 cancer stem-like cell death with silybin encapsulated in polymersomes and deregulation of stemness-related miRNAs and their potential targets [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Cancer stem cells (CSCs) have powerful self-renewal ability and tumor recurrence. Pancreatic ductal adenocarcinoma is a malignancy with high mortality rate and ˃5% survival. Silybin has anticancer and hepatoprotective properties.
Fatemeh Tehrani +3 more
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Faraday Discussions, 2008 Polymersomes are vesicles whose membranes are comprised of self-assembled amphiphilic block co-polymers. Synthetic control of block co-polymer chemistry provides an advantageous diversity of polymersome functions, ranging from tunable materials strength, superior encaspulation of hydrophobic and hydrophilic drugs and optical dyes, and facile ...
Daniel A, Hammer +8 more
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Molecules, 2022 Limited tissue selectivity and targeting of anticancer therapeutics in systemic administration can produce harmful side effects in the body. Various polymer nano-vehicles have been developed to encapsulate therapeutics and prevent premature drug release.
Veronika Kozlovskaya +6 more
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Polymersomes Eradicating Intracellular Bacteria [PDF]
ACS Nano, 2020 Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These professional phagocytes can be parasitized by intracellular bacteria, turning them from housekeepers to hiding places and favoring chronic and/or disseminated infection.
Fenaroli F. +18 more
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DNA-tethered Polymersome Clusters as Nanotheranostic Platform
CHIMIA, 2021 Nanotheranostics combine the use of nanomaterials and biologically active compounds to achieve diagnosis and treatment at the same time. To date, severe limitations compromise the use of nanotheranostic systems as potent nanomaterials are often ...
Claire E. Meyer +4 more
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Adaptive Polymersome Nanoreactors [PDF]
ChemNanoMat, 2019 AbstractAdaptive polymersome systems have gained much interest in a wide variety of research fields, ranging from cell mimics to nanomedicine, because of their high stability, tunable shape and size. Furthermore, polymersomes can be effectively transformed into nanoreactors via the incorporation of catalytic species. By employing polymersomes which are
Che, Hailong, van Hest, Jan C. M.
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Coronal Complexation Induces Snowman-Shaped Janus Polymersome Formation. [PDF]
Angew Chem Int Ed EnglLai RY, Wong CK, Stenzel MH.
europepmc +3 more sources
Paramagnetic Porous Polymersomes [PDF]
Langmuir, 2008 The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents.
Cheng, Zhiliang, Tsourkas, Andrew
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Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
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