Results 31 to 40 of about 3,055 (192)

DENV-Mimetic Polymersome Nanoparticles Bearing Multi-Epitope Lipopeptides Antigen as the Next-Generation Dengue Vaccine

Pharmaceutics, 2022
Dengue remains a severe threat to public health. The safety and efficacy of the licensed dengue vaccine is not clinically satisfactory, which necessitate the need of new approach in designing an effective dengue vaccine without eliciting adverse reaction.
Nur Adilah Abdul Rahman, Abdin Shakirin Mohamad Norpi, Muhammad Luqman Nordin, Mohd Cairul Iqbal Mohd Amin, Abdullah Al-Hadi Ahmad Fuaad, Nor Azila Muhammad Azami, Nirmal Marasini, Fazren Azmi   +7 more
doaj   +1 more source

Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region

Pharmaceutics, 2021
Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula, Amir Sadeghi Boroujeni, Shoupeng Cao, Shirin Tavakoli, Roxane Ridolfo, Elisa Toropainen, Marika Ruponen, Jan C. M. van Hest, Arto Urtti   +8 more
doaj   +1 more source

“Clickable” polymersomes

Chemical Communications, 2007
Polymersomes, composed of amphiphilic polystyrene-block-poly(acrylic acid) (PS-b-PAA), with the periphery being covered with azide groups, were used for further functionalization using "click" chemistry.
Opsteen, J.A., Brinkhuis, R.P., Teeuwen, R.L.M., Lowik, D.W.P.M., Hest, J.C.M. van   +4 more
openaire   +3 more sources

Butyrylcholinesterase-Loaded Liposomes and Polymersomes: Catalytic Parameters for Three Types of Substrates. [PDF]

Int J Mol Sci
Shaihutdinova Z, Batasheva S, Masson P, Pashirova T.   +3 more
europepmc   +3 more sources

Hydrogel-polymersome composites as a sensing platform for monitoring food spoilage. [PDF]

Nanoscale
John C, Dos Santos EC, Wehr RP, Messmer D, Palivan CG, Dinu IA.   +5 more
europepmc   +3 more sources

Toward Functional Synthetic Cells: In‐Depth Study of Nanoparticle and Enzyme Diffusion through a Cross‐Linked Polymersome Membrane

Advanced Science, 2019
Understanding the diffusion of nanoparticles through permeable membranes in cell mimics paves the way for the construction of more sophisticated synthetic protocells with control over the exchange of nanoparticles or biomacromolecules between different ...
Hannes Gumz, Susanne Boye, Banu Iyisan, Vera Krönert, Petr Formanek, Brigitte Voit, Albena Lederer, Dietmar Appelhans   +7 more
doaj   +1 more source

Morphogenesis of starfish polymersomes

Nature Communications, 2023
AbstractThe enhanced membrane stability and chemical versatility of polymeric vesicles have made them promising tools in micro/nanoreactors, drug delivery, cell mimicking, etc. However, shape control over polymersomes remains a challenge and has restricted their full potential.
Jiawei Sun, Sandra Kleuskens, Jiabin Luan, Danni Wang, Shaohua Zhang, Wei Li, Gizem Uysal, Daniela A. Wilson   +7 more
openaire   +5 more sources

Photoactivated Polymersome Nanomotors: Traversing Biological Barriers [PDF]

Angewandte Chemie International Edition, 2020
AbstractSynthetic nanomotors are appealing delivery vehicles for the dynamic transport of functional cargo. Their translation toward biological applications is limited owing to the use of non‐degradable components. Furthermore, size has been an impediment owing to the importance of achieving nanoscale (ca.
Jingxin Shao, Shoupeng Cao, David S. Williams, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest   +4 more
openaire   +5 more sources

Photopolymerization-Induced Polymersome Rupture [PDF]

Langmuir, 2019
Poly(butadiene)- b-poly(ethylene oxide) (PBut2.5- b-PEO1.3) giant polymersomes were prepared using an emulsion-centrifugation method. The impact of a fast decrease of the osmotic pressure inside the lumen of giant PBut- b-PEO vesicles was studied by confocal microscopy. This osmotic imbalance was created by performing the photoinduced polymerization of
Sophie C. Larnaudie, Ariane Peyret, Louis Beauté, Pierre Nassoy, Sébastien Lecommandoux   +4 more
openaire   +2 more sources

Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy

Nature Communications, 2021
Induced motion has emerged as a method to increase the efficacy of delivery and therapeutic outcomes using nanomaterials. Here, the authors report on a Janus gold shell polymersome with aggregation-induced emission molecules for phototactic and ...
Shoupeng Cao, Jingxin Shao, Hanglong Wu, Shidong Song, Maria Teresa De Martino, Imke A. B. Pijpers, Heiner Friedrich, Loai K. E. A. Abdelmohsen, David S. Williams, Jan C. M. van Hest   +9 more
doaj   +1 more source