Results 41 to 50 of about 3,055 (192)
Apoptosis induction and proliferation inhibition by silibinin encapsulated in nanoparticles in MIA PaCa-2 cancer cells and deregulation of some miRNAs [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Silibinin, as an herbal compound, has anti-cancer activity. Because of low solubility of silibinin in water and body fluids, it was encapsulated in polymersome nanoparticles and its effects were evaluated on pancreatic cancer cells and ...
Fatemeh Khakinezhad Tehrani +3 more
doaj +1 more source
Generating biomembrane-like local curvature in polymersomes via dynamic polymer insertion
Nature Communications, 2021 Investigating biomembrane curvature formation is important for studying intracellular processes, but the instability of liposome models mimicking these membranes restricts exploration of membrane processes.
Jiawei Sun +4 more
doaj +1 more source
Cascade Reactions in Multicompartmentalized Polymersomes [PDF]
Angewandte Chemie, 2013 AbstractEnzyme‐filled polystyrene‐b‐poly(3‐(isocyano‐L‐alanyl‐aminoethyl)thiophene) (PS‐b‐PIAT) nanoreactors are encapsulated together with free enzymes and substrates in a larger polybutadiene‐b‐poly(ethylene oxide) (PB‐b‐PEO) polymersome, forming a multicompartmentalized structure, which shows structural resemblance to the cell and its organelles. An
Peters, R.J.R.W. +6 more
openaire +4 more sources
Frontiers in Chemical Engineering, 2022 GM1 gangliosidosis is a lysosomal storage disorder caused by deficiency of β-galactosidase (βgal) and subsequent accumulation of GM1 ganglioside in lysosomes. One of the pathological aspects of GM1 gangliosidosis, and other storage disorders, is impaired
Bipin Chakravarthy Paruchuri +3 more
doaj +1 more source
Development of a Polymersome Blood Ammonia Assay Coupled with a Portable Near-Infrared Fluorometer [PDF]
ACS Bio & Med Chem AuMarie-Lynn Al-Hawat +3 more
doaj +2 more sources
Polymerization-Induced Polymersome Fusion [PDF]
Journal of the American Chemical Society, 2019 The dynamic interactions of membranes, particularly their fusion and fission, are critical for the transmission of chemical information between cells. Fusion is primarily driven by membrane tension built up through membrane deformation. For artificial polymersomes, fusion is commonly induced via the external application of a force field. Herein, fusion-
Spyridon Varlas +5 more
openaire +3 more sources
Hydrophilic Janus Micelles From an ABC Triblock Copolymer
Angewandte Chemie, EarlyView.An amphiphilic triblock copolymer with poly(ethylene glycol) (PEG) and poly(N‐vinylpyrrolidone) (PVP) coronas self‐assembles into spherical micelles with Janus‐type surface segregation in water. Cryo‐TEM, enabled by selective PVP labeling, and 1H‐NOESY NMR reveal phase separation.
José Muñoz‐López +5 more
wiley +2 more sources
Advanced Science, 2021 The challenge of effective integration and use of artificial organelles with orthogonal‐responsive membranes and their communication in eukaryotic protocells is to understand the intrinsic membrane characteristics.
Xueyi Wang +7 more
doaj +1 more source
Electromechanical Limits of Polymersomes [PDF]
Physical Review Letters, 2001 Physical Review ...
Aranda-Espinoza, Helim +3 more
openaire +4 more sources
The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]
PLoS ONE, 2016 Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene +5 more
doaj +1 more source