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Characterization of Gramicidin A in Triblock and Diblock Polymersomes and Hybrid Vesicles via Continuous Wave Electron Paramagnetic Resonance Spectroscopy [PDF]
BiomimeticsStudying membrane proteins in a native environment is crucial to understanding their structural and/or functional studies. Often, widely accepted mimetic systems have limitations that prevent the study of some membrane proteins.
Emma A. Gordon +3 more
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Light-Triggered Polymersome-Based Anticancer Therapeutics Delivery
Nanomaterials, 2022 Polymersomes are biomimetic cell membrane-like model structures that are self-assembled stepwise from amphiphilic copolymers. These polymeric (nano)carriers have gained the scientific community’s attention due to their biocompatibility, versatility, and ...
Elisa Hernández Becerra +3 more
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Polymersomes in “Gelly” Polymersomes: Toward Structural Cell Mimicry [PDF]
Langmuir, 2011 We demonstrate here the formation of compartmentalized polymersomes with an internal "gelly" cavity using an original and versatile process. Nanosize polymersomes of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA), formed by a solvent displacement method are encapsulated with a rough "cytoplasm mimic" in giant polymersomes of poly ...
Maïté Marguet +2 more
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Drug Delivery, 2021 Radiotherapy (RT) is a frequently used means in clinical tumor treatment. The outcome of RT varies, however, to a great extent, due to RT resistance or intolerable dose, which might be resolved by the development of radio-sensitizing strategies. Here, we
Zhehong Zhu +9 more
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Metabolically Active, Fully Hydrolysable Polymersomes [PDF]
Angewandte Chemie International Edition, 2019 AbstractThe synthesis and aqueous self‐assembly of a new class of amphiphilic aliphatic polyesters are presented. These AB block polyesters comprise polycaprolactone (hydrophobe) and an alternating polyester from succinic acid and an ether‐substituted epoxide (hydrophile).
Yunqing Zhu +6 more
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Morphogenesis of starfish polymersomes
Nature Communications, 2023 The enhanced membrane stability and chemical versatility of polymeric vesicles have made them promising tools in micro/nanoreactors, drug delivery, cell mimicking, etc. However, shape control over polymersomes remains a challenge and has restricted their
Jiawei Sun +7 more
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Click Chemistry in Polymersome Technology
PharmaceuticalsPolymersomes, self-assembled nanoparticles composed of amphiphilic block copolymers, have emerged as promising versatile nanovesicles with various applications, such as drug delivery, medical imaging, and diagnostics.
Nuno M. Saraiva +3 more
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Polymersomes Based Versatile Nanoplatforms for Controlled Drug Delivery and Imaging [PDF]
Advanced Pharmaceutical Bulletin, 2023 Drug delivery systems made based on nanotechnology represent a novel drug carrier system that can change the face of therapeutics and diagnosis. Among all the available nanoforms polymersomes have wider applications due to their unique characteristic ...
Rohini Kotha +4 more
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Pharmaceutics, 2021 Posterior eye tissues, such as retina, are affected in many serious eye diseases, but drug delivery to these targets is challenging due to various anatomical eye barriers.
Vijayabhaskarreddy Junnuthula +8 more
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Inherently Fluorescent Peanut-Shaped Polymersomes for Active Cargo Transportation
Pharmaceutics, 2023 Nanomotors have been extensively explored for various applications in nanomedicine, especially in cargo transportation. Motile properties enable them to deliver pharmaceutical ingredients more efficiently to the targeted site. However, it still remains a
Jianhong Wang +6 more
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