Results 11 to 20 of about 4,829 (203)

Co-delivery of anti-inflammatory and antioxidant agents via polymersomes for osteoarthritis therapy [PDF]

Frontiers in Pharmacology
BackgroundOsteoarthritis (OA) is a chronic degenerative joint disease primarily driven by inflammation and oxidative stress. This study aimed to develop a polymersome-based co-delivery system encapsulating hydrophilic cordycepin and hydrophobic ...
Mengjie Rui, Li Wang, Ke Mi, Yinfeng Li, Naying Fang, Yingying Ge, Qiuqi Feng, Yaqi Luo, Chunlai Feng, Chunlai Feng   +9 more
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Butyrylcholinesterase-Loaded Liposomes and Polymersomes: Catalytic Parameters for Three Types of Substrates [PDF]

Int J Mol Sci
Zukhra Shaihutdinova, Svetlana Batasheva, Patrick Masson, Tatiana N. Pashirova   +3 more
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Hallmarks of Polymersome Characterization [PDF]

ACS Materials Au
Polymersomes have the potential to become the next generation of vesicular drug delivery systems. Their high chemical versatility and in certain cases higher membrane stability than liposomes raised the high hopes for polymersomes as a drug carrier, but the clinical translation has been slow.
Matoori S.
openaire   +4 more sources

Designing polymersomes with surface-integrated nanoparticles through hierarchical phase separation [PDF]

Nature Communications
Polymersomes with surface-integrated nanoparticles, in which a smaller sphere is attached to a larger capsule, are typically formed through complex processes like membrane deformation, polymerization, or membrane functionalization.
Jingxin Shao, Yingtong Luo, Hanglong Wu, Jianhong Wang, Xuan Zhou, Süleyman Er, Shoupeng Cao, Hongyu Sun, H. Hugo Pérez Garza, Hongkui Zheng, Heiner Friedrich, Loai K. E. A. Abdelmohsen, Jan C. M. van Hest   +12 more
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Polymersomes as a potential platform for cancer immunotherapy

Materials Today Advances, 2022
With the focus in the field of cancer nanomedicine shifting from direct tumor targeting to modulation of the immune system, new opportunities arise for the employment of nanocarrier systems.
J.F. Scheerstra, A.C. Wauters, J. Tel, L.K.E.A. Abdelmohsen, J.C.M. van Hest   +4 more
doaj   +1 more source

Triggered Polymersome Fusion

Journal of the American Chemical Society, 2023
The contents of biological cells are retained within compartments formed of phospholipid membranes. The movement of material within and between cells is often mediated by the fusion of phospholipid membranes, which allows mixing of contents or excretion of material into the surrounding environment.
Stephen D. P. Fielden, Matthew J. Derry, Alisha J. Miller, Paul D. Topham, Rachel K. O’Reilly   +4 more
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Leuko-polymersomes [PDF]

Faraday Discussions, 2008
Polymersomes are vesicles whose membranes are comprised of self-assembled amphiphilic block co-polymers. Synthetic control of block co-polymer chemistry provides an advantageous diversity of polymersome functions, ranging from tunable materials strength, superior encaspulation of hydrophobic and hydrophilic drugs and optical dyes, and facile ...
Daniel A, Hammer, Gregory P, Robbins, Jered B, Haun, John J, Lin, Wei, Qi, Lee A, Smith, P Peter, Ghoroghchian, Michael J, Therien, Frank S, Bates   +8 more
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Coronal Complexation Induces Snowman‐Shaped Janus Polymersome Formation [PDF]

Angew Chem Int Ed Engl
Martina H. Stenzel, Rebecca Y. Lai, Chin Ken Wong   +2 more
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Dynamic metastable polymersomes enable continuous flow manufacturing

Nature Communications, 2023
Polymersomes are polymeric analogues of liposomes with exceptional physical and chemical properties. Despite being dubbed as next-generation vesicles since their inception nearly three decades ago, polymersomes have yet to experience translation into the
Chin Ken Wong, Rebecca Y. Lai, Martina H. Stenzel   +2 more
doaj   +1 more source

Fabrication of Polymersomes: A Macromolecular Architecture in Nanotherapeutics

Chemistry, 2022
In consideration of the issues of drug delivery systems, the artificial vesicle structures composed of block copolymers called polymersomes recently gained considerable attention.
Pragya Pallavi, Karthick Harini, Pemula Gowtham, Koyeli Girigoswami, Agnishwar Girigoswami   +4 more
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