Results 21 to 30 of about 4,829 (203)
Polymersomes Eradicating Intracellular Bacteria [PDF]
ACS Nano, 2020 Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These professional phagocytes can be parasitized by intracellular bacteria, turning them from housekeepers to hiding places and favoring chronic and/or disseminated infection.
Fenaroli F. +18 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 Polymersomes are nanometric vesicles that can encapsulate large and hydrophilic biomolecules, such as proteins, in the aqueous core. Data in literature show large variation in encapsulation efficiency (%EE) values depending on the method used for ...
Jorge Javier Muso-Cachumba +3 more
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The Role of Membrane Fluidization in the Gel-Assisted Formation of Giant Polymersomes. [PDF]
PLoS ONE, 2016 Polymersomes are being widely explored as synthetic analogs of lipid vesicles based on their enhanced stability and potential uses in a wide variety of applications in (e.g., drug delivery, cell analogs, etc.).
Adrienne C Greene +5 more
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Adaptive Polymersome Nanoreactors [PDF]
ChemNanoMat, 2019 AbstractAdaptive polymersome systems have gained much interest in a wide variety of research fields, ranging from cell mimics to nanomedicine, because of their high stability, tunable shape and size. Furthermore, polymersomes can be effectively transformed into nanoreactors via the incorporation of catalytic species. By employing polymersomes which are
Che, Hailong, van Hest, Jan C. M.
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A mathematical investigation into the uptake kinetics of nanoparticles in vitro.
PLoS ONE, 2021 Nanoparticles have the potential to increase the efficacy of anticancer drugs whilst reducing off-target side effects. However, there remain uncertainties regarding the cellular uptake kinetics of nanoparticles which could have implications for ...
Hannah West +8 more
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Paramagnetic Porous Polymersomes [PDF]
Langmuir, 2008 The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents.
Cheng, Zhiliang, Tsourkas, Andrew
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The Impact of MiR-33a-5p Inhibition in Pro-Inflammatory Endothelial Cells
Diseases, 2023 Evidence suggests cholesterol accumulation in pro-inflammatory endothelial cells (EC) contributes to triggering atherogenesis and driving atherosclerosis progression.
Kun Huang +8 more
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Engineering Polymersome Protocells [PDF]
The Journal of Physical Chemistry Letters, 2011 The field of biomimicry is embracing the construction of complex assemblies that imitate both biological structure and function. Advancements in the design of these mimetics have generated a growing vision for creating an artificial or proto- cell. Polymersomes are vesicles that can be made from synthetic, biological or hybrid polymers and can be used ...
Neha P, Kamat +2 more
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Photo-Responsive Polymersomes as Drug Delivery System for Potential Medical Applications
Molecules, 2020 Due to a strong retardation effect of o-nitrobenzyl ester on polymerization, it is still a great challenge to prepare amphiphilic block copolymers for polymersomes with a o-nitrobenzyl ester-based hydrophobic block.
Wanting Hou +5 more
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Bio-Inspired Polymersome Nanoreactors [PDF]
CHIMIA, 2019 Abstract: Two key concepts in living organisms are that biochemical reactions are sequestered into reaction compartments such as cells and organelles, and that many of the complex biological reaction cascades involve transient activation of reactions in response to external triggers. Here we review our efforts to implement these concepts into
Rifaie-Graham, Omar +2 more
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