Results 71 to 80 of about 20,043 (225)

Variations in the diacylglycerol acyltransferase-1 (DGAT1) and its association with meat tenderness in Gannan yaks (Bos grunniens)

open access: yesItalian Journal of Animal Science, 2020
Diacylglycerol acyltransferase-1 (DGAT1) has been recognised as one of the functional genes during fat deposition and closely related to meat quality.
Xiaoli Gao   +8 more
doaj   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

open access: yesExploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen   +8 more
wiley   +1 more source

Molecular characterization of drug-resistant and drug-sensitive Aspergillus isolates causing infectious keratitis

open access: yesIndian Journal of Ophthalmology, 2011
Purpose: To study the susceptibilities of Aspergillus species against amphotericin B in infectious keratitis and to find out if drug resistance had any association with the molecular characteristics of the fungi.
Niranjan Nayak   +5 more
doaj   +1 more source

Identification of SNPs and expression patterns of FZD3 gene and its effect on wool traits in Chinese Merino sheep (Xinjiang Type)

open access: yesJournal of Integrative Agriculture, 2019
As a member of the Frizzled family, Frizzled3 (FZD3) is a receptor of the canonical Wnt signaling pathway and plays a vital role in mammalian hair follicle developmental processes. However, its effects on wool traits are not clear. The objectives of this
Bing-ru ZHAO   +11 more
doaj   +1 more source

Assembly and Maturation of a T = 4 Quasi-Equivalent Virus Is Guided by Electrostatic and Mechanical Forces [PDF]

open access: yes, 2014
Nudaurelia capensis w virus (NωV) is a eukaryotic RNA virus that is well suited for the study of virus maturation. The virus initially assembles at pH 7.6 into a marginally stable 480-Å procapsid formed by 240 copies of a single type of protein subunit ...
Bradley Kearney   +5 more
core   +1 more source

Plasmonics‐Enhanced Characterization of Cervid PrP (87–114) Fragment Aggregates in Solution

open access: yesJournal of Biophotonics, EarlyView.
Multimodal nanophotonics platform combining plasmon‐enhanced imaging, label‐free SERS, and optical staining reveals new insights into the aggregation of the cervid PrP (87–114) fragment, an amyloidogenic sequence linked to chronic wasting disease susceptibility.
Shinki Midha   +4 more
wiley   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei   +7 more
wiley   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

open access: yesMed Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li   +8 more
wiley   +1 more source

Identification of Ovine KRTAP28-1 and Its Association with Wool Fibre Diameter

open access: yesAnimals, 2019
Keratin-associated proteins (KAPs) are a diverse group of proteins and form a matrix that cross-links keratin intermediate filaments in hair and wool fibres.
Lingrong Bai   +5 more
doaj   +1 more source

Az öröklött és szerzett kataláz hiány klinikai és klinikai biokémiai vonatkozásai = Clinical and biochemical consequences of inherited and acquired forms of catalase deficiency [PDF]

open access: yes, 2007
A hidrogénperoxid az élőszervezetekre gyakorolt oxidatív, toxikus hatásáról volt ismert, míg szerepe az újabb irodalmi adatok alapján átértékelődött.
Góth, László   +3 more
core  

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