Results 61 to 70 of about 11,434 (195)
iMetaOmics, EarlyView.Shotgun metagenomics and culture‐based isolate genomics revealed position‐associated high‐risk antibiotic resistance genes (ARGs) signals across poultry manure piles and surrounding soils. Culture‐confirmed Enterobacteriaceae and IncHI2A‐related blaNDM‐5 plasmid backgrounds further highlight priority host‐ARG‐plasmid contexts for farm antimicrobial ...
Yaling Wang +5 more
wiley +1 more source
Investigation of plasma protein binding and nephrotoxicity of polymyxins
, 2017 The use of the polymyxin antibiotics (colistin [polymyxin E] and polymyxin B) declined soon after their approval in the 1950s due to the high incidence of nephrotoxicity and neurotoxicity, and the availability of ‘less toxic’ therapeutic options that had
Azad, Mohammad Abul Kalam (3750883)
core +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Background This study evaluated the antimicrobial activity of thyme essential oil (TEO) encapsulated in electrospun zein fibers for use in bilayer films as active packaging for cherry tomatoes. The antimicrobial activity of TEO and bilayer films with 20%, 40%, and 60% TEO was assessed with agar diffusion and microatmosphere assays.
Jéssica Silveira Vitoria +7 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Polymyxins -a review focusing on their nePhrotoxicity
, 2020 Polymyxins are polypeptide antibiotics with strong action against Gram-negative bacteria. Their use was almost halted between 1970 and 1980 with the advent of less toxic compounds.
Carlos Alberto Caldeira Mendes +1 more
core
Recent advances and perspectives in the design and development of polymyxins
, 2017 Polymyxins: background and future perspectives. Introducing metabolism and detoxification considerations into the design of new polymyxins to reduce nephrotoxicity.
Yolanda Cajal, Francesc Rabanal
core +1 more source
ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii
mLife, EarlyView.Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei +7 more
wiley +1 more source
Enhancing the antibacterial activity of polymyxins using a nonantibiotic drug
, 2019 Malathy Krishnamurthy,1 Margaret M Lemmon,1 Evan M Falcinelli,1 Reuel A Sandy,1 Jennifer N Dootz,1 Tiffany M Mott,1 Sathish Rajamani,1,2 Kurt E Schaecher,3 Allen J Duplantier,1,4 Rekha G Panchal11Department of Target Discovery and Experimental ...
Rajamani S +9 more
core
Pediatric Discovery, EarlyView.Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Small, EarlyView.This review provides a systematic overview of the field of antibacterial PhotoDynamic Therapy (aPDT) triggered by upconversion nanoparticles (UCNPs), focusing on the mechanisms and the key factors that define their efficacy for generating bactericidal species upon NIR‐light activation.
Zhe Li +3 more
wiley +1 more source