Results 21 to 30 of about 6,269 (253)

Streptomyces RNases – Function and impact on antibiotic synthesis

open access: yesFrontiers in Microbiology, 2023
Streptomyces are soil dwelling bacteria that are notable for their ability to sporulate and to produce antibiotics and other secondary metabolites. Antibiotic biosynthesis is controlled by a variety of complex regulatory networks, involving activators ...
George H. Jones
doaj   +1 more source

The discovery of the mechanisms of biological synthesis of nucleic acids: 1959 Nobel laureates S. Ochoa and A. Kornberg [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2021
Alongside the chemical and physical research of nucleic acids in the 1940s-50s, the mechanisms of their biosynthesis were investigated. Thus, in 1959, Severo Ochoa and Arthur Kornberg were awarded the Nobel Prize in Physiology or Medicine for the ...
O. P. Matyshevska   +2 more
doaj   +1 more source

Regulation of miRNA content. Part 2. Degradation of miRNAs

open access: yesZdorovʹe Rebenka, 2021
The scientific review presents the process of regulation of microRNA content — microRNA degradation. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The ...
A.E. Abaturov, V.L. Babуch
doaj   +1 more source

Papel de la enzima PNPasa en el transporte de ARNmt en cáncer linfático: Revisión bibliográfica [PDF]

open access: yes, 2021
Lymphoma is the most common type of blood cancer today and, as its name suggests, it begins in the lymphatic system. The origin of this disease is related to mitochondrial defects, generated by mutations in the PNPase enzyme or polynucleotide ...
Lizanda Piqueras, Myriam   +1 more
core   +1 more source

Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli. [PDF]

open access: hybridJ Biol Chem, 2011
Nurmohamed S   +9 more
europepmc   +3 more sources

RNase III participates in control of quorum sensing, pigmentation and oxidative stress resistance in Rhodobacter sphaeroides

open access: yesMolecular Microbiology, Volume 120, Issue 6, Page 874-892, December 2023., 2023
New functions for endoribonuclease III were unravelled in the facultative photosynthetic bacterium Rhodobacter sphaeroides by transcriptome analysis and phenotypic screening under three different growth conditions. The RNase III deficient mutant showed reduced pigmentation, linked to decreased expression of photosynthesis‐related mRNAs (bch and crt ...
Janek Börner   +2 more
wiley   +1 more source

A Novel Pathway of Functional microRNA Uptake and Mitochondria Delivery

open access: yesAdvanced Science, Volume 10, Issue 24, August 25, 2023., 2023
In the presence of serum, microRNAs (miRNAs) spontaneously form ≈110 nm nanoparticles, mediated bycationic proteins. When depleted, miRNA uptake is blocked. Unlike lysosome‐located, nanoparticle‐delivere mechanism are preferentially delivered to mitochondria of recipient cells by PNPT1.
Jiachen Liu   +13 more
wiley   +1 more source

Mitochondrial DNA is a target of HBV integration

open access: yesCommunications Biology, 2023
Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear.
Domenico Giosa   +14 more
doaj   +1 more source

PNPase and RhlB Interact and Reduce the Cellular Availability of Oxidized RNA in Deinococcus radiodurans

open access: yesMicrobiology Spectrum, 2022
8-Oxo-7,8-dihydroguanine (8-oxoG) is a major RNA modification caused by oxidative stresses and has been implicated in carcinogenesis, neurodegeneration, and aging.
Runhua Han   +3 more
doaj   +1 more source

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