Results 51 to 60 of about 43,981 (239)

RNase III participates in control of quorum sensing, pigmentation and oxidative stress resistance in Rhodobacter sphaeroides

open access: yesMolecular Microbiology, Volume 120, Issue 6, Page 874-892, December 2023., 2023
New functions for endoribonuclease III were unravelled in the facultative photosynthetic bacterium Rhodobacter sphaeroides by transcriptome analysis and phenotypic screening under three different growth conditions. The RNase III deficient mutant showed reduced pigmentation, linked to decreased expression of photosynthesis‐related mRNAs (bch and crt ...
Janek Börner   +2 more
wiley   +1 more source

PNPase and RhlB Interact and Reduce the Cellular Availability of Oxidized RNA in Deinococcus radiodurans

open access: yesMicrobiology Spectrum, 2022
8-Oxo-7,8-dihydroguanine (8-oxoG) is a major RNA modification caused by oxidative stresses and has been implicated in carcinogenesis, neurodegeneration, and aging.
Runhua Han   +3 more
doaj   +1 more source

A Novel Pathway of Functional microRNA Uptake and Mitochondria Delivery

open access: yesAdvanced Science, Volume 10, Issue 24, August 25, 2023., 2023
In the presence of serum, microRNAs (miRNAs) spontaneously form ≈110 nm nanoparticles, mediated bycationic proteins. When depleted, miRNA uptake is blocked. Unlike lysosome‐located, nanoparticle‐delivere mechanism are preferentially delivered to mitochondria of recipient cells by PNPT1.
Jiachen Liu   +13 more
wiley   +1 more source

How hydrolytic exoribonucleases impact human disease: Two sides of the same story

open access: yesFEBS Open Bio, Volume 13, Issue 6, Page 957-974, June 2023., 2023
Ribonucleases (or simply RNases) are the enzymes responsible for the processing and degradation of all types of RNAs, having multiple roles in every aspect of RNA metabolism. Here, we review what is known about the involvement of the RNase II/RNB family of 3′–5′ exoribonucleases in human disease.
Susana M. Costa   +4 more
wiley   +1 more source

Adenovirus-mediated hPNPase(old-35) gene transfer as a therapeutic strategy for neuroblastoma [PDF]

open access: yes, 2009
Current treatment options for neuroblastoma fail to eradicate the disease in the majority of high-risk patients, clearly mandating development of innovative therapeutic strategies. Gene therapy represents a promising approach for reversing the neoplastic
Ardelt   +37 more
core   +2 more sources

MSP1 encodes an essential RNA‐binding pentatricopeptide repeat factor required for nad1 maturation and complex I biogenesis in Arabidopsis mitochondria

open access: yesNew Phytologist, Volume 238, Issue 6, Page 2375-2392, June 2023., 2023
Summary Mitochondrial biogenesis relies on nuclearly encoded factors, which regulate the expression of the organellar‐encoded genes. Pentatricopeptide repeat (PPR) proteins constitute a major gene family in angiosperms that are pivotal in many aspects of mitochondrial (mt)RNA metabolism (e.g. trimming, splicing, or stability).
Corinne Best   +9 more
wiley   +1 more source

Isolate Specific Cold Response of Yersinia enterocolitica in Transcriptional, Proteomic, and Membrane Physiological Changes [PDF]

open access: yes, 2020
Yersinia enterocolitica, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the Y. enterocolitica cold response.
Alter, Thomas   +4 more
core   +1 more source

Symbiont‐specific responses to environmental cues in a threesome lichen symbiosis

open access: yesMolecular Ecology, Volume 32, Issue 5, Page 1045-1061, March 2023., 2023
Abstract Photosymbiodemes are a special case of lichen symbiosis where one lichenized fungus engages in symbiosis with two different photosynthetic partners, a cyanobacterium and a green alga, to develop two distinctly looking photomorphs. We compared gene expression of thallus sectors of the photosymbiodeme‐forming lichen Peltigera britannica ...
Jasmin Almer   +5 more
wiley   +1 more source

The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half, which is sufficient for degradosome assembly [PDF]

open access: yes, 1998
Escherichia coli RNase E, an essential single-stranded specific endoribonuclease, is required for both ribosomal RNA processing and the rapid degradation of mRNA.
Jakobsen, J.S.   +5 more
core   +2 more sources

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