Results 51 to 60 of about 6,269 (253)

SP1 and NFY Regulate the Expression of PNPT1, a Gene Encoding a Mitochondrial Protein Involved in Cancer [PDF]

, 2022
The Polyribonucleotide nucleotidyltransferase 1 gene (PNPT1) encodes polynucleotide phosphorylase (PNPase), a 30-50 exoribonuclease involved in mitochondrial RNA degradation and surveillance and RNA import into the mitochondrion.
Gómez Tatay, Lucia, Hernández Andreu, José Miguel, Prieto Ruiz, Jesús Ángel, Revert Ros, Fernando, Revert Ros, Francisco, Ventura González, Ignacio   +5 more
core   +1 more source

Kinetic studies on the phosphorolysis of polynucleotides by polynucleotide phosphorylase

Journal of Biological Chemistry, 1975
The kinetics of the phosphorolysis of polynucleotide (as differentiated from oligonucleotide) by polynucleotide phosphorylase of Micrococcus luteus has been investigated. Double reciprocal plots of initial velocity against either inorganic phosphate or polynucleotide concentration are linear, and furthermore, the affinity of the enzyme for either ...
J Y Chou, P McPhie, M F Singer
openaire   +2 more sources

Stochastic sensing of polynucleotides using patterned nanopores [PDF]

Phys. Rev. X 2, 021002 (2012), 2012
The effect of the microscopic structure of a pore on polymer translocation is studied using Langevin dynamics simulation, and the consequence of introducing patterned stickiness inside the pore is investigated. It is found that the translocation process is extremely sensitive to the detailed structure of such patterns with faster than exponential ...
arxiv   +1 more source

Enzymatic Synthesis and Fractionation of Fluorescent PolyU RNAs

Bio-Protocol, 2018
The physical properties of viral-length polyuridine (PolyU) RNAs, which cannot base-pair and form secondary structures, are compared with those of normal-composition RNAs, composed of comparable numbers of each of A, U, G and C nucleobases.
Christian Beren, Katherine Liu, Lisa Dreesens, Charles Knobler, William Gelbart   +4 more
doaj   +1 more source

RNase E and the High-Fidelity Orchestration of RNA Metabolism. [PDF]

, 2018
The bacterial endoribonuclease RNase E occupies a pivotal position in the control of gene expression, as its actions either commit transcripts to an irreversible fate of rapid destruction or unveil their hidden functions through specific processing ...
Aguirre, Apirion, Apirion, Arraiano, Aït-Bara, Aït-Bara, Aït-Bara, Baker, Bandyra, Bandyra, Bandyra, Barria, Bernstein, Bonneau, Borowski, Bossche, Bouvier, Boël, Bruce, Callaghan, Callaghan, Cameron, Carabetta, Carpousis, Carpousis, Castello, Chandran, Chao, Chao, Cheng, Christiansen, Chujo, Clarke, Coburn, Commichau, Condon, Cormack, De Lay, Deana, Del Campo, Dendooven, Dendooven, Desnoyers, Deutscher, Deutscher, Dubey, Durand, Duss, Ehretsmann, Even, Fei, Gao, Garrey, Ghora, Ghora, Go, Gonzalez, Gorski, Gottesman, Górna, Górna, Göpel, Halbach, Hardwick, Hardwick, Holmqvist, Hotto, Iost, Irie, Kaberdin, Kaberdin, Kawamoto, Khemici, Khemici, Khemici, Khemici, Kim, Kim, Kime, Kime, Koch, Komarova, Koslover, Li, Li, Lin, Mackie, Mackie, Mackie, Marcaida, Massé, Massé, McDowall, McDowall, Michaux, Miczak, Misra, Mizuno, Moffitt, Mohanty, Moll, Montero Llopis, Morita, Morita, Murashko, Nurmohamed, O'Hara, Ow, Ow, Pfeiffer, Prud'homme-Généreux, Purusharth, Py, Razew, Saramago, Shahbabian, Sittka, Smirnov, Smirnov, Stead, Strahl, Sulthana, Suzuki, Symmons, Symmons, Tamura, Thompson, Tree, Tsai, Vanderpool, Voss, Wagner, Walter, Wang, Wasmuth, Waters, Waters, Wellington, Westermann, Zhang   +139 more
core   +1 more source

RNase E biomolecular condensates stimulate PNPase activity

Scientific Reports, 2023
Bacterial Ribonucleoprotein bodies (BR-bodies) play an essential role in organizing RNA degradation via phase separation in the cytoplasm of bacteria. BR-bodies mediate multi-step mRNA decay through the concerted activity of the endoribonuclease RNase E ...
Michael J. Collins, Dylan T. Tomares, Vidhyadhar Nandana, Jared M. Schrader, W. Seth Childers   +4 more
doaj   +1 more source

Genome wide association studies for acid phosphatase activity at varying phosphorous levels in Brassica juncea L

Frontiers in Plant Science, 2022
Acid phosphatases (Apases) are an important group of enzymes that hydrolyze soil and plant phosphoesters and anhydrides to release Pi (inorganic phosphate) for plant acquisition. Their activity is strongly correlated to the phosphorus use efficiency (PUE)
Priyanka Upadhyay, Mehak Gupta, Simarjeet Kaur Sra, Rakesh Sharda, Sanjula Sharma, Virender K. Sardana, Javed Akhatar, Gurpreet Kaur   +7 more
doaj   +1 more source

Transient expression of βC1 protein differentially regulates host genes related to stress response, chloroplast and mitochondrial functions [PDF]

, 2010
Background Geminiviruses are emerging plant pathogens that infect a wide variety of crops including cotton, cassava, vegetables, ornamental plants and cereals.
Amin, Imran, Andleeb, Saiqa, Bashir, Aftab, Briddon, Rob W, Mansoor, Shahid   +4 more
core   +3 more sources

A PNPase dependent CRISPR System in Listeria. [PDF]

PLoS Genetics, 2014
The human bacterial pathogen Listeria monocytogenes is emerging as a model organism to study RNA-mediated regulation in pathogenic bacteria. A class of non-coding RNAs called CRISPRs (clustered regularly interspaced short palindromic repeats) has been ...
Nina Sesto, Marie Touchon, José Marques Andrade, Jiro Kondo, Eduardo P C Rocha, Cecilia Maria Arraiano, Cristel Archambaud, Éric Westhof, Pascale Romby, Pascale Cossart   +9 more
doaj   +1 more source

Analysis of mRNA Decay Intermediates in Bacillus subtilis 3′ Exoribonuclease and RNA Helicase Mutant Strains

mBio, 2022
The Bacillus subtilis genome encodes four 3′ exoribonucleases: polynucleotide phosphorylase (PNPase), RNase R, RNase PH, and YhaM. Previous work showed that PNPase, encoded by the pnpA gene, is the major 3′ exonuclease involved in mRNA turnover; in a ...
Shivani Chhabra, Zachary F. Mandell, Bo Liu, Paul Babitzke, David H. Bechhofer   +4 more
doaj   +1 more source