Results 91 to 100 of about 127,781 (261)

The Impact of Cooking on Antioxidant and Enzyme Activities in Ruichang Yam Polyphenols

Foods
In this study, the total polyphenol content (TPC), total flavonoid content (TFC), and biological activity of yam polyphenols (including free phenolics, conjugated phenolics, and bound phenolics) were investigated during home cooking.
Haoping Liu, Hua Zhang, Mengting Geng, Dingxin Shi, Dongsheng Liu, Yanxiao Jiao, Zhiqiang Lei, You Peng   +7 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Axial Boron Coordination Reconstructs Stereostructure of Cu Single‐Atom Nanozymes for Efficient Water‐Phase Chemical Sensing

Angewandte Chemie, EarlyView.
Sun et al. proposed an axial boron coordination strategy to reconstruct the stereostructure of Cu SAzymes and enable them to serve as efficient laccase mimics for high‐throughput smart sensor array detection of phenolic pollutants in water phases. ABSTRACT Developing single‐atom nanozymes with stereoconfigurations is a new paradigm for biomimetic ...
Qijun Sun, Hongyu Shi, Si Liu, Ziping Li, Yu Yang, Fengwang Li, Wenli Wu, Qiongzheng Hu, Kang Liang   +8 more
wiley   +2 more sources

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Metal–Phenolic Complexation Governs Soil Mineral Crystallinity to Enhance Crop Growth

Advanced Science, EarlyView.
A coordination‐driven, coprecipitation approach is presented to obtain polyphenolic‐incorporated minerals with tunable crystallinity, offering insights into how plants may influence soil mineral structures. Soil minerals can incorporate polyphenolic secondary metabolites and enhance plant nutrition by facilitating the formation of amorphous metal ...
Jong‐Rok Jeon, Omid Mazaheri, Tianzheng Wang, Ali Zavabeti, Ho Young Yoon, Nguyen Thanh Phong, Eun‐Nam Joe, Zhixing Lin, Shuaijun Pan, Chan‐Jin Kim, Frank Caruso   +10 more
wiley   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

Advanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin, Sisi Chen, Shengli Huang, Mengqi Huang, Jingyan Zhu, Zijian Wang, Jianliang Shen, Qinxiang Zheng   +7 more
wiley   +1 more source

Agronomic and Nutritional Perspectives on Vegetable Crops in Africa

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Vegetable production plays a key role in food security, nutrition, and livelihoods across Africa. Moreover, African indigenous vegetables emerge as underutilized yet highly valuable crops, rich in macro‐ and micronutrients, as well as bioactive compounds with an array of health benefits.
Đorđe Vojnović, Pamela Owusu Osei, Sina Siavash Moghaddam, Issiake Konate, Jelena Popović‐Đorđević   +4 more
wiley   +1 more source

Liquid–Liquid Equilibrium Data for Refined Olive Pomace Oil + Oleic Acid + Ethanol + Water Systems: Application to Solvent Deacidification

Journal of the American Oil Chemists' Society, EarlyView.
ABSTRACT This study presents the first experimental liquid–liquid equilibrium (LLE) data for quaternary systems composed of refined olive pomace oil, oleic acid, ethanol, and water at 303.15 K. These data are essential for the design and optimization of solvent‐based deacidification processes, particularly for oils with high free fatty acid (FFA ...
Jacqueline Mansano Ortega, Andresa Feihrmann, Guilherme Duenhas Machado, Lucio Cardozo‐Filho, Francisco Adrian Sánchez, Vladimir Ferreira Cabral   +5 more
wiley   +1 more source