Results 81 to 90 of about 1,949 (187)
ABSTRACT The current trend of individualized food items (nutrient content and flavor) can be particularly valuable to support people's health and well‐being in isolated environments where access to fresh foods and diverse nutrition is difficult. At the same time, bioactive compounds and micronutrients can be employed to countermeasure any health ...
Svenja Schmidt +4 more
wiley +1 more source
Anaphylaxis and the inclusion of polysorbates in biotherapeutics
Both unwanted immunogenicity and anaphylaxis comprise major components of safety assessment, however, few if any attempts are made to differentiate drug-related from excipient-related anaphylaxis.
Edward Maggio
doaj
Intravitreal injection of polysorbate 80: a functional and morphological study
Objective : to determine the functional and morphological effects at rabbits retina of PS80 concentration used in the preparation of intravitreal drugs. Methods: eleven New Zealand rabbits received a intravitreal injection of 0.1ml of PS80.
FRANCISCO MAX DAMICO +8 more
doaj +1 more source
DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li +11 more
wiley +1 more source
The flow of this trial and the treatment schedule of adjuvant chemotherapy with nedaplatin plus docetaxel for completely resected non‐small cell lung cancer (NSCLC) (A). The primary endpoint of this study was tolerability, assessed by the completion rate of the planned four chemotherapy cycles. As a result, it was 74.3%, exceeding that reported for the
Koji Teramoto +9 more
wiley +1 more source
We developed a rapid method using variable pathlength UV spectrometry combined with a slope-intercept strategy to quantify polysorbates in complex in-process formulation buffers for biologics manufacturing.
Guanglou Cheng +5 more
doaj +1 more source
DETERMINATION OF POLYSORBATES BY SPECTROPHOTOMETRY IN DRUGS BASED ON RECOMBINANT PROTEINS
Method of determination of polysorbate 20 and polysorbate 80 in recombinant protein drugs based on spectrophotometry has been designed. Isolation of polysorbate from solution is carried out by solid phase extraction followed by elution of polysorbate ...
A. D. Askretkov +3 more
doaj
Monoclonal antibodies (mAbs) are powerful therapeutic agents known for their high specificity and effectiveness in treating complex diseases. Yet, one of their major challenges is their tendency to aggregate, which can reduce treatment efficacy and even ...
Deta Almira +3 more
doaj +1 more source
From Composition to Function: Defining Functional Equivalence in Plant‐Based Meat Analogs
Sustainable Food Proteins, Volume 4, Issue 3, September 2026.
Akila Srinivasagam Ramasamy Venkateswaran +1 more
wiley +1 more source
Biopharmaceuticals are the fastest‐growing class of drugs in the healthcare industry, but their global reach is severely limited by their propensity for rapid aggregation.
Alexander N. Prossnitz +7 more
doaj +1 more source

