Results 61 to 70 of about 9,191 (255)

Detergent Virus Inactivation in Chromatography Systems

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Detergent treatment is a widely utilized virus‐inactivation step in therapeutic protein manufacturing to safeguard products. Traditionally, this operation is performed in an incubation vessel in batch mode. In this investigation, a methodology was developed to enable virus inactivation via a post‐load, detergent‐containing wash within a bind ...
Kang Cai   +6 more
wiley   +1 more source

DETERMINATION OF POLYSORBATE IN BIOTECH DRUGS

open access: yesРазработка и регистрация лекарственных средств, 2019
The article is a review of publications on the quantitative determination of polysorbates in pharmaceuticals. The author touches upon the structure and properties of polysorbates.
V. I. Grokhovskiy   +4 more
doaj  

Scientific Opinion on the re‐evaluation of polyoxyethylene sorbitan monolaurate (E 432), polyoxyethylene sorbitan monooleate (E 433), polyoxyethylene sorbitan monopalmitate (E 434), polyoxyethylene sorbitan monostearate (E 435) and polyoxyethylene sorbitan tristearate (E 436) as food additives

open access: yesEFSA Journal, 2015
The Panel on Food Additives and Nutrient Sources added to Food (ANS) re‐evaluated the safety of polysorbate 20 (E 432), polysorbate 80 (E 433), polysorbate 40 (E 434), polysorbate 60 (E 435) and polysorbate 65 (E 436) as food additives.
EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS)
doaj   +1 more source

Allergy to COVID-19 vaccines: A current update

open access: yesAllergology International, 2021
Adverse allergic reactions due to the administration of the vaccines developed for the protection of coronavirus disease 2019 (COVID-19) have been reported since the initiation of the vaccination campaigns.
Beatriz Cabanillas, Natalija Novak
doaj   +1 more source

The Role of Polysorbate 80 and HPβCD at the Air-Water Interface of IgG Solutions [PDF]

open access: yes, 2018
Purpose: To test the hypothesis of surface displacement as the underlying mechanism for IgG stabilization by polysorbates and HPβCD against surface-induced aggregation.
Besheer, Ahmed   +4 more
core  

Enzymatic synthesis of sugar esters and their potential as surface-active stabilizers of coconut milk emulsions [PDF]

open access: yes, 2012
Sugar esters are compounds with surfactant properties (biosurfactants), i.e., capable of reducing the surface tension and promote the emulsification of immiscible liquids.
Gonçalves, Luciana Rocha Barros   +6 more
core   +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann   +3 more
wiley   +1 more source

Microemulsions for colorectal cancer treatments: general considerations and formulation of methotrexate [PDF]

open access: yes, 2016
[Abstract] Microemulsions combine the advantages of emulsions with those of nanocarriers, overcoming the stability problems of the former and providing facile scalable systems with compartments adequate for high drug loadings.
Concheiro, Ángel   +6 more
core   +2 more sources

Ucuúba Fat (Virola surinamensis) and Cellulose Nanocrystals Functionalizing Cassava (Manihot esculenta)  Starch Films

open access: yesChemFoodChem, EarlyView.
Cassava starch films were functionalized with Ucuúba fat and cellulose nanocrystals to tailor wettability, optical, mechanical, and barrier properties. Integrating Amazonian bioresources with nanotechnology enables sustainable edible coatings with tunable performance for fresh food preservation and enhanced UV protection.
Geovana Cristina Pinto Rodrigues   +4 more
wiley   +1 more source

Dispersants and Seafood Safety Assessment of the potential impact of Corexit® oil dispersants on seafood safety [PDF]

open access: yes, 2011
The April 20, 2010 explosion and subsequent sinking of the Deepwater Horizon oil production platform (DWH) resulted in the largest oil spill in U.S. history.
Dickey, Robert W., Dickhoff, Walton W.
core   +1 more source

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