Results 41 to 50 of about 9,191 (255)

Prediction of long-term polysorbate degradation according to short-term degradation kinetics

mAbs, 2023
Polysorbates (PSs) are a class of surfactants commonly used in the formulation of protein therapeutic agents to provide protection against denaturation and aggregation. When the PS in these drug formulations degrades, loss of stabilization of the protein
Sisi Zhang, Caterina Riccardi, Dane Carlson, Douglas Kamen, Kenneth S. Graham, Mohammed Shameem, Hanne Bak, Hui Xiao, Ning Li   +8 more
doaj   +1 more source

Development of a Potentiometric Sensor Sensitive to Polysorbate 20 [PDF]

, 2019
Polyoxyethylated sorbitans (polysorbates) are widely used in the chemical, pharmaceutical, and cosmetic industries, but only quantitative determination is used mainly for chromatographic methods.
Kotok, V. (Valerii), Kovalenko, V. (Vadym), Labyak, O. (Oksana), Mironyak, M. (Maria), Volnyanska, O. (Olena)   +4 more
core   +2 more sources

Photoacoustic Sentinel Lymph Node Imaging with Self-Assembled Copper Neodecanoate Nanoparticles [PDF]

, 2012
Photoacoustic tomography (PAT) is emerging as a novel, hybrid, and non-ionizing imaging modality because of its satisfactory spatial resolution and high soft tissue contrast. PAT combines the advantages of both optical and ultrasonic imaging methods.
Angana Senpan, Bigall N. C., Brewer G. J., Cady B., Cai X., Ceren Yalaz, Crouse C., de la Zerda A., Dipanjan Pan, Gregory M. Lanza, Haffty B. G., Karthik Omanakuttan, Kim C., Kim J. W., Krag D., Li M. L., Li Y., Lihong V. Wang, Link S., Lisiecki I., Melancon M. P., Pan D., Pan D., Pan D., Pramanik M., Purushotham A. D., Samuel A. Wickline, Song K. H., Song K. H., Song K. H., Ung O. A., Veronesi U., Wang X. D., Wang X. D., Williams G. L., Xin Cai   +35 more
core   +1 more source

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release [PDF]

, 2011
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug ...
A Al-Omar, A Latrofa, A Miro, A Trapani, A Vyas, AC Jain, AK Upadhyay, AL Nielsen, AS Hoffman, B Haeberlin, B Pose-Vilarnovo, BN Naidu, C Cannavà, C Rodriguez-Tenreiro, C Rupp, C-Y Chen, Catarina Carvalho, Claúdia Conduto, CM Buchanan, CM Fernandes, D Duchêne, D Duchêne, EA Zannou, EY Kim, F Frézard, F Hirayama, G Corti, G Gladys, G Pescitelli, G Trapani, G Wenz, G Zingone, GL Amidon, H Blode, H Hamada, H Matsuda, H Namazi, H Taira, H Yano, HA Archontaki, Helena M. Cabral Marques, HH Sigurdsson, HS Ganapathy, HS Woldum, Inês Sanches, IV Terekhova, J Cheng, J Králová, J Savolainen, J Szejtli, J Szejtli, J Xiong, JJ García-Rodriguez, João Arrais, JP Venter, JR Moyano, JS Smith, JW Wong, K Dua, K Minami, K Motoyama, K Nakanishi, K Okimoto, K Okimoto, K Okimoto, K Terao, K Udo, K Uekama, K Uekama, K Uekama, K-H Frӧmming, KP Chowdary, L Ribeiro, L Szente, L Trichard, M Agüeros, M Agüeros, M Charoenchaitrakool, M Cirri, M Echezarreta-López, M Fukuda, M Jug, M Jug, M Kamada, M Prabaharan, M Roux, M Sauceau, M Temtem, M Türk, M Usuda, M Yoshinari, M-J Zou, ME Zugasti, MT Esclusa-Díaz, MZI Khan, N Mourtzis, N Patel, N Zerrouk, N Zhang, N Özdemir, P Jansook, P Mura, P Mura, P Mura, P Mura, P Mura, Patrícia Pontes, Paulo José Salústio, PJ Salústio, R Cavalli, R Cavalli, R Challa, R Ficarra, R Garg, R Stancanelli, RL Carrier, S Petralito, S Péroche, S Sajeesh, S Sotthivirat, S Sotthivirat, S Szejtli, S Tommasini, S-Y Lee, Shishu, SM Badr-Eldin, T Endo, T Higashi, T Higashi, T Irie, T Loftsson, T Loftsson, T Loftsson, T Vasconcelos, T Yamanoi, V Burckbuchler, V Lemesle-Lamache, VM Rao, W Ling, W Sajomsang, X Lu, X Wen, X-M Liu, Y He, Y Ikeda, Y Ikeda, Y Liu, Y Liu, Y Lu, Y Tozuka, Y Zhou, Y-Z Du, Z Lu, Z Wang   +153 more
core   +1 more source

Antimicrobial Activity of Polysorbate 80-iodine Complex: Polysorbate 80 Firmly Retains Iodine

Journal of Oleo Science, 2022
Considering that iodine is highly volatile and has low solubility in water, it is utilized as an antiseptic in its complex form (iodophor) with a carrier material. Herein, we prepared the polysorbate 80-iodine complex and investigated its properties.
Shigekazu Yano, Senri Terada, Misaki Fukushi, Yuitsu Otsuka, Satomi Mizunuma, Satoshi Asakura, Takahiro Kawai, Hiroyuki Konno, Masatoshi Endo, Yoshimune Nonomura   +9 more
openaire   +2 more sources

Effects of emulsifiers on the moisture sorption and crystallization of amorphous sucrose lyophiles

Food Chemistry: X, 2019
The crystallization of amorphous sucrose can be problematic in food products. This study explored how emulsifiers (a range of sucrose esters, polysorbates, and soy lecithin) impact the moisture sorption and crystallization of amorphous sucrose lyophiles.
Adrienne L. Voelker, Gianna Verbeek, Lynne S. Taylor, Lisa J. Mauer   +3 more
doaj   +1 more source

Characterization, physicochemical stability, and evaluation of in vitro digestibility of solid lipid microparticles produced with palm kernel oil and tristearin [PDF]

, 2014
Solid lipid particles have been investigated by food researchers due to their ability to enhance the incorporation and bioavailability of lipophilic bioactives in aqueous formulations.
Borrin, Thais Ribeiro, Brito, Thais Carvalho, Pinheiro, A. C., Pinho, Samantha Cristina de, Ruy, Pâmela, Silva, Janaina Costa da, Vicente, A. A.   +6 more
core   +3 more sources

Evaluating ginger extract, wild blueberry extract, and polysorbates (PS20, PS80) on Pseudomonas aeruginosa biofilm formation

Journal of Infection in Developing Countries, 2018
Introduction: Pseudomonas aeruginosa is a biofilm forming pathogen that challenges clinical and industrial settings. Many natural products and surfactants have been screened and valued for their anti-biofilm capacity.
Mariam Miari, Sari Shawki Rasheed, Nathaline Haidar-Ahmad, Antoine Abou Fayad, Ghassan M Matar   +4 more
doaj   +1 more source

High throughput multidimensional liquid chromatography approach for online protein removal and characterization of polysorbates and poloxamer in monoclonal antibody formulations.

Journal of Chromatography A
The majority of commercially available monoclonal antibody (mAb) formulations are stabilized with one of three non-ionic surfactants: polysorbate 20 (PS20), polysorbate 80 (PS80), or poloxamer 188 (P188).
M. M. Zegota, Georg Schuster, M. De Pra, Tibor Müllner, T. Menzen, Frank Steiner, Andrea Hawe   +6 more
semanticscholar   +1 more source

Mechanisms of crystallisation in polysorbates and sorbitan esters

CrysteEngComm, 2020
Solid-state behaviour of the commonly used pharmaceutical excipient polysorbates, and their non-ethoxylated equivalents.
Emelie J. Nilsson, T. Lind, D. Scherer, Tatyana Skansberger, K. Mortensen, J. Engblom, V. Kocherbitov   +6 more
semanticscholar   +1 more source