Correction: Kumar et al. Harnessing Potential of ω-3 Polyunsaturated Fatty Acid with Nanotechnology for Enhanced Breast Cancer Therapy: A Comprehensive Investigation into ALA-Based Liposomal PTX Delivery. <i>Pharmaceutics</i> 2024, <i>16</i>, 913. [PDF]
Kumar R +11 more
europepmc +1 more source
Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley +1 more source
A PUFA-rich diet increases endogenous genotoxic stress and mitochondrial DNA damage in mice. [PDF]
Shimizu M +4 more
europepmc +1 more source
The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo +11 more
wiley +1 more source
Fatty Acid Profile of Table Grapes: Impact of Cultivar and Fruit Protection on Saturated, Monounsaturated, and Polyunsaturated Fatty Acid Profile. [PDF]
Coronel Montesdeoca NT +4 more
europepmc +1 more source
Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi +6 more
wiley +1 more source
Long-chain polyunsaturated fatty acids and school achievement: tales of a tangled web. [PDF]
Colombo J, Carlson SE.
europepmc +1 more source
Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa +18 more
wiley +1 more source
Long-Chain Fatty Acids as Drivers of Neuroinflammation in Neurodegeneration: Mechanistic Links to Lipid Peroxidation, Ferroptosis, and Mitochondrial Dysfunction. [PDF]
Christodoulou RC +3 more
europepmc +1 more source
Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
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