Results 121 to 130 of about 7,969,000 (286)
Facile synthesis of PEI-based crystalline templated mesoporous silica with molecular chirality for improved oral delivery of the poorly water-soluble drug. [PDF]
Drug Deliv, 2021 Xin W +8 more
europepmc +1 more source
Strategies for formulating and delivering poorly water-soluble drugs
, 2015 Water solubility is a key parameter in drug formulation since it highly influences drug pharmacokinetics and pharmacodynamics. In the past decades, the challenge with poorly water soluble drugs has been growing continuously.
Rodriguez Aller, Marta Ruth +3 more
core +1 more source
Inverse Design of Nanoparticulate Materials
Advanced Materials, EarlyView.Inverse design shifts nanomaterial development from empirical trial‐and‐error to predictive model‐driven strategies. It can rely on knowledge‐based, data‐based, or hybrid process and property functions. This perspective article provides a practical framework for applying inverse design based on instructive examples. It discusses which modeling approach
Nabi Etienne Traoré +5 more
wiley +1 more source
, 2010 A major hurdle in pharmaceutical formulation is water insolubility of most of drugs affecting their stability and bioavailability. If the drug is also insoluble in organic medium, it is difficult to deliver it in a sufficiently bioavailable form and ...
Hiren Bechra +3 more
core +1 more source
Advanced Materials, EarlyView.Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol +16 more
wiley +1 more source
Solid dispersion: A promising technique to enhance solubility of poorly water soluble drug [PDF]
, 2011 Poorly water soluble compounds have solubility and dissolution related bioavailability problems. The present review deals in detail about solid dispersion technology and its manufacturing techniques at laboratory and industrial level.
Sharma, Anshu; Bhupal Nobles’ College of Pharmacy, Udaipur - 313 001, Rajasthan, India. +1 more
core +2 more sources
ENHANCING SOLUBILITY: INNOVATIVE APPROACHES TO ENHANCE SOLUBILITY OF POORLY WATER-SOLUBLE DRUG [PDF]
This investigation aimed to determine the effectiveness of innovative method by using single or double combinatorial technique approach in preparing a solid matrix to enhance the aqueous solubility and dissolution of poorly water-soluble drugs like ...
NEELAM YADAV, HARINATH DWIVEDI
core +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Advanced Materials, EarlyView.Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
Solid Dispersions of Poorly Water Soluble Drug Using Spray Drying Technique [PDF]
, 2013 The basic objectives of this study were to prepare and characterize solid dispersions of poorly water-soluble drug fluconazole using hydrophilic carriers by spray drying technique.
V, Patil Manisha; Department Of Pharmaceutics, Tatayasaheb Kore College of Pharmacy, Warananagar +4 more
core +2 more sources
Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen
Advanced Materials, EarlyView.Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang +5 more
wiley +1 more source