Improved Bioavailability of Poorly Water-Soluble Drug by Targeting Increased Absorption through Solubility Enhancement and Precipitation Inhibition. [PDF]
Pharmaceuticals (Basel), 2021 Lee JH +5 more
europepmc +1 more source
Novel hydrogels based on polysaccharides for soft tissue regeneration: preparation and characterization [PDF]
, 2015 Předložená diplomová práce se zabývá přípravou, síťováním a fyzikálně-chemickou charakterizací hydrogelů na bázi polysacharidů. Cílem práce bylo vyvinout elastické filmy, které by mohly být použity pro vlhké hojení ran.
Nedomová, Eva
core
Cytotoxicity micropollutant removal in a crossflow membrane bioreactor [PDF]
, 2011 The application of membrane bioreactor (MBR) technology was investigated with the aim of evaluating its potential for cytostatic drug and cytotoxicity bioremoval. The toxicity removal was assessed from biomarker test. CP removal of up to 80% was achieved
Albasi, Claire +6 more
core +2 more sources
Choline-Amino Acid Ionic Liquids as Green Functional Excipients to Enhance Drug Solubility
Pharmaceutics, 2018 The development of effective forms to incorporate poorly soluble drugs into delivery systems remains a problem. Thus, it is important to find alternatives such as finding excipients that increase drug solubility. Ionic liquids (ILs), particularly choline-
Rita Caparica +6 more
doaj +1 more source
DEVELOPMENT OF SUSTAINED RELEASE TABLETS CONTAINING SOLID DISPERSIONS OF BACLOFEN [PDF]
Journal of Fundamental and Applied Sciences, 2013 Sustained release tablets containing solid dispersions granules of a poorly water soluble drug were prepared to investigate the controlled release of the drug.
K. H. Janardhana +4 more
doaj
Facile synthesis of PEI-based crystalline templated mesoporous silica with molecular chirality for improved oral delivery of the poorly water-soluble drug. [PDF]
Drug Deliv, 2021 Xin W +8 more
europepmc +1 more source
Layered double hydroxides-indomethacin nanohybrids: intercalation, pH influence, stability and release properties [PDF]
, 2016 In this work, three pH values (8, 9 and 10) were studied for the insertion of Indomethacin (Indo) molecules into Layered Double Hydroxides (LDHs). The obtained results showed that the LDH materials have been a good storage for the drug.
Crivello, Mónica Elsie +6 more
core +1 more source
Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]
, 2012 The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core +1 more source
Oléagineux, Corps gras, Lipides, 2010 Labrasol® and Gelucire® 44/14 are lipid-based excipients used for the oral drug delivery of poorly water-soluble drugs. These macrogolglycerides are composed of acylglycerols and PEG esters, potential substrates of digestive lipases.
Fernandez Sylvie +2 more
doaj +1 more source
Ileo-Colon Targeting of the Poorly Water-Soluble Drug Celecoxib Using a pH-Dependent Coating in Combination with Self-Emulsifying Drug Delivery or Solid Dispersion Systems. [PDF]
Pharmaceutics, 2021 Broesder A +5 more
europepmc +1 more source