Results 21 to 30 of about 147,210 (303)

Curcumin-loaded zeolite as anticancer drug carrier: Effect of curcumin adsorption on zeolite structure [PDF]

open access: yes, 2020
In this work we used a combination of different techniques to investigate the adsorption properties of curcumin by zeolite type A for potential use as an anticancer drug carrier.
Ahali Abadeh, Z.   +3 more
core   +1 more source

Solubility and Stability of Some Pharmaceuticals in Natural Deep Eutectic Solvents-Based Formulations

open access: yesMolecules, 2021
Some medicines are poorly soluble in water. For tube feeding and parenteral administration, liquid formulations are required. The discovery of natural deep eutectic solvents (NADES) opened the way to potential applications for liquid drug formulations ...
Natali Rianika Mustafa   +4 more
doaj   +1 more source

The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl [PDF]

open access: yes, 2014
The cogrinding technique is one of most effective methods for improving the dissolution of poorly water-soluble drugs and it is superior to other approaches from an economical as well as an environmental standpoint, as the technique does not require any ...
Ali Nokhodchi   +8 more
core   +1 more source

Nanosuspension: An approach to enhance solubility of drugs

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2011
One of the major problems associated with poorly soluble drugs is very low bioavailability. The problem is even more complex for drugs like itraconazole, simvastatin, and carbamazepine which are poorly soluble in both aqueous and nonaqueous media ...
Vishal R Patel, Y K Agrawal
doaj   +1 more source

Preparation of ethylcellulose/methylcellulose blends by supercritical antisolvent precipitation [PDF]

open access: yes, 2006
The supercritical antisolvent (SAS) techniquewas used to prepare ethyl cellulose/methyl cellulose blends, two biocompatible polymers commonly used as drug carriers in controlled delivery systems. Ethyl cellulose is widely used as a drug carrier.
Cardoso, M. Margarida   +4 more
core   +1 more source

Solubility improvement of progesterone from solid dispersions prepared by solvent evaporation and co-milling [PDF]

open access: yes, 2020
The aim of this contribution was to evaluate the impact of processing methods and polymeric carriers on the physicochemical properties of solid dispersions of the poorly soluble drug progesterone (PG). Five polymers: hydroxypropyl methylcellulose (HPMC),
Al-Obaidi, Hisham   +3 more
core   +1 more source

Synthesis of mesoporous silica nanoparticles and drug loading of poorly water soluble drug cyclosporin A

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Mesoporous silica nanoparticles (MSNs) are introduced as chemically and thermally stable nanomaterials with well-defined and controllable morphology and porosity.
A Lodha   +6 more
doaj   +1 more source

Silodosin oral films: Development, physico-mechanical properties and in vitro dissolution studies in simulated saliva [PDF]

open access: yes, 2019
Sublingual film dosage forms for drugs used for fast symptomatic treatment have promise because they allow a rapid onset of action. The aim of this study was to prepare films of silodosin intended for sublingual administration for the symptomatic ...
Adair   +57 more
core   +2 more sources

Automation potential of a new, rapid, microscopy based method for screening drug-polymer solubility [PDF]

open access: yes, 2020
For the pharmaceutical industry, the preformulation screening of the compatibility of drug and polymeric excipients can often be time-consuming because of the use of trial-and-error approaches.
Alhijjaj, Muqdad   +4 more
core   +1 more source

Solubility Enhancement of Poorly Water Soluble Drug

open access: yes, 2023
The Biopharmaceutical Classification System includes solubility as one of its core criteria, and dissolution rate is the most crucial variable affecting a drug's bioavailability. A weakly water-soluble medication is defined as a substance with a solubility of less than 1 part per 10,000 parts of water.
Madkaikar, S.A., Shukla, U.D.
openaire   +1 more source

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