Results 31 to 40 of about 7,280,281 (268)
Lipid nanoparticles for the delivery of poorly water-soluble drugs [PDF]
Journal of Pharmacy and Pharmacology, 2010 Abstract Objectives This review discusses important aspects of lipid nanoparticles such as colloidal lipid emulsions and, in particular, solid lipid nanoparticles as carrier systems for poorly water-soluble drugs, with a main focus on the parenteral and peroral use of these carriers.
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Nanosuspension: An emerging trend to improve solubility of poorly water soluble drugs [PDF]
, 2019 There are various parameters like solubility, stability, compatibility, excipient, and photostability which affects formulation of drugs, but solubility plays an important role for drug formulation. Most of newly discovered drugs are poorly water soluble.
Vedaga, S. B. +2 more
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Solubility Enhancement of Poorly Water Soluble Drug
, 2023 The Biopharmaceutical Classification System includes solubility as one of its core criteria, and dissolution rate is the most crucial variable affecting a drug's bioavailability. A weakly water-soluble medication is defined as a substance with a solubility of less than 1 part per 10,000 parts of water.
Madkaikar S.A., Shukla U.D.
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Pharmaceutics, 2023 The biopharmaceutical classification system groups low-solubility drugs into two groups: II and IV, with high and low permeability, respectively. Most of the new drugs developed for common pathologies present solubility issues.
María Elena Gamboa-Arancibia +6 more
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Self - Emulsifying Drug Delivery System: A Novel Approach for Oral Delivery of Poorly Water Soluble Drugs [PDF]
Records of Pharmaceutical & Biomedical Sciences, 2021 Self nano emulsifying drug delivery systems (SNEDDs) gained much attention in the last decades since, such systems considered one of the most favorable and efficient approaches to enhance solubility, increase drug absorption and hence, enhance its oral ...
Ahmed Nasef
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, 2020 Supporting data for the publication "Dual stimuli-responsive hydrogel for improved colon-targeted delivery of poorly water-soluble ...
Wylie, Matthew; id_orcid +6 more
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Particle Engineering Techniques: A Boon in Enhancing Dissolution Rate of Poorly Water Soluble Drugs [PDF]
, 2019 For any dosage forms enhancing dissolution is the first criteria i.e. it should give increased bioavailability in order to provide onset of action. In market many poorly soluble drugs are available which are having problem of low solubility.
Manohara Sai, T., Santosh Kumar, Rada
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Pharmaceutics, 2023 The prevalence of active pharmaceutical ingredients (APIs) with low water solubility has experienced a significant increase in recent years. These APIs present challenges in formulation, particularly for oral dosage forms, despite their considerable ...
Arif Budiman +8 more
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Pharmaceutics, 2010 Several biologically relevant phospholipids were assessed as potential carriers/additives for rapidly dissolving solid formulations of piroxicam (Biopharmaceutics Classification System Class II drug).
Muhammad D. Hussain +4 more
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Molecules, 2021 The most important task in the design of dosage forms is to modify the pharmaceutical substances structure in order to increase solubilization, targeted delivery, controlled rate of drug administration, and its bioavailability.
Elena V. Uspenskaya +3 more
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