Results 101 to 110 of about 5,282,511 (279)

Multi-method survey rediscovers critically endangered species and strengthens Madagascar's freshwater fish conservation

Scientific Reports
Freshwater ecosystems are crucial for global biodiversity through supporting plant and animal species and providing essential resources. These ecosystems are under significant threat, particularly in island environments such as Madagascar.
Cintia Oliveira Carvalho, Melina Pazirgiannidi, Tsilavina Ravelomanana, Fetra Andriambelomanana, Audun Schrøder-Nielsen, Jonathan Stuart Ready, Hugo de Boer, Charles-Edouard Fusari, Quentin Mauvisseau   +8 more
doaj   +1 more source

Co-occurrence of depression, anxiety and increased alcohol use during the late stage of the COVID-19 pandemic in Saskatchewan, Canada: a cross-sectional survey

BMJ Public Health
Background Impact of the COVID-19 pandemic on mental health and substance use is well recognised. COVID-19 impacted Saskatchewan particularly hard as it has a higher prevalence of alcohol consumption than the national average.
Erika Dyck, James Dixon, Nazeem Muhajarine, Daniel A Adeyinka, Md Sabbir Ahmed, Ali Bukhari, Jim Clifford, Gabriela Novotna   +7 more
doaj   +1 more source

Meeting the Needs of Central American Migrant Youth in Schools [PDF]

, 2019
The goal of this qualitative inquiry was to explore the barriers that Central American migrant youth face in California education settings while using the power of participatory action research to harness the direct voices of this unique and rapidly ...
Aguilar, Amy, Lopez, Desiree, Millan, Laurie   +2 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Legofit: estimating population history from genetic data

BMC Bioinformatics, 2019
Background Our current understanding of archaic admixture in humans relies on statistical methods with large biases, whose magnitudes depend on the sizes and separation times of ancestral populations.
Alan R. Rogers
doaj   +1 more source

[Review of] Barry T. Klein. Reference Encyclopedia of the American Indian [PDF]

, 1988
First published in 1967, this is an indispensable resource for information about the current Indian population and its affairs. The title may be misleading since information about the Canadian Indian population is also provided.
Kachel, Douglas
core   +1 more source

Can one hear the shape of a population history?

, 2014
Reconstructing past population size from present day genetic data is a major goal of population genetics. Recent empirical studies infer population size history using coalescent-based models applied to a small number of individuals. Here we provide tight
Kim, Junhyong, Mossel, Elchanan, Ross, Nathan, Rácz, Miklós Z.   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A Biogeographic History of the Plains Bison Focusing on Population and Range Dynamics [PDF]

, 2015
Early bison originated in Asia and migrated to North America by means of the Bering Land Bridge, which opened around 600,000 years ago. Just after the Wisconsin glaciation (11, 700 years ago), there were two allopatric species of bison residing in North ...
Roman, Grace
core   +2 more sources