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The porcine cytomegalovirus (PCMV) will not stop xenotransplantation
Xenotransplantation, 2022Joachim Denner
exaly +3 more sources
Porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV): A threat for xenotransplantation?
Xenotransplantation, 2022 AbstractThe potential for a donor‐derived transmission of porcine cytomegalovirus/porcine roseolovirus (PCMV/PRV) to the recipient has been recognized since pigs were considered candidate donors for xenotransplantation. This review gives a short description of the viral properties and summarizes the current evidence of the effects of PCMV/PRV ...
Joachim Denner
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Xenotransplantation and porcine cytomegalovirus
Xenotransplantation, 2015AbstractPorcine microorganisms may be transmitted to the human recipient when xenotransplantation with pig cells, tissues, and organs will be performed. Most of such microorganisms can be eliminated from the donor pig by specified or designated pathogen‐free production of the animals.
Joachim Denner
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Genomic organization and molecular characterization of porcine cytomegalovirus
Virology, 2014 A strain of the porcine cytomegalovirus (PCMV), which causes inclusion body rhinitis in newborn piglets, has been characterized with respect to its complete genome sequence. The virus genome is 128,367bp, containing 79 predicted open reading frames (ORFs).
Xinna Ge, Xin Guo, Lei Zhou
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Porcine Cytomegalovirus Infection in Wild Boars
Nippon Juishikai Zasshi Journal of the Japan Veterinary Medical Association, 2013 Tomoyuki Shibahara +2 more
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Isolation and Experimental Infection with Porcine Cytomegalovirus
Zentralblatt für Veterinärmedizin Reihe B, 1977SummaryFive strains of porcine cytomegalovirus (PCMV) were isolated in cultures of pig lung macrophages (PLM) from pigs aged about 3 weeks. Two of them were isolated from the nasal mucosa and the remaining three from the lung. The presence of PCMV in PLM cultures was demonstrated indirectly by staining and directly by electron microscopy.
L, Valícek, B, Smíd, J, Mensík
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In situ hybridization and immunohistochemistry for the detection of porcine cytomegalovirus
Journal of Virological Methods, 2012To establish in situ hybridization and immunohistochemistry based-assays for the detection of porcine cytomegalovirus, routinely processed renal tissue sections from 34 diseased piglets suspected of having the infection were obtained and examined. Using hematoxylin and eosin, porcine cytomegalovirus inclusion bodies were found in the nucleus of renal ...
Tomoyuki Shibahara +2 more
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Porcine cytomegalovirus (PCMV) in early gestation
Veterinary Microbiology, 1988Following intranasal exposure to PCMV at or within 48 h of coitus transplacental infection occurred in two groups of gilts. Five out of 22 embryos were infected in the first group but only 2 out of 63 in the second. A more rapid immune response as measured by circulating antibody was probably instrumental in abrogating infection in the second group. In
N, Edington, A E, Wrathall, J T, Done
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Journal of Virological Methods, 2007
The use of porcine organs is being developed as a means to alleviate the shortage of human organs for transplantation. Recommendations have been published for the microbiological specifications of organ-source pigs to reduce the possibility of a microorganism from pigs being inadvertently transferred to the recipient of the xenograft.
Bokyu Kang, Bongkyun Park
exaly +3 more sources
The use of porcine organs is being developed as a means to alleviate the shortage of human organs for transplantation. Recommendations have been published for the microbiological specifications of organ-source pigs to reduce the possibility of a microorganism from pigs being inadvertently transferred to the recipient of the xenograft.
Bokyu Kang, Bongkyun Park
exaly +3 more sources