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Differences between xenotransplantation and allogeneic kidney transplantation: the current situation and future challenges in Japan. [PDF]
Matsumura S +8 more
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Research landscapes and knowledge structure of cardiac xenotransplantation: A bibliometric analysis. [PDF]
Li S +10 more
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Xenotransplantation and porcine cytomegalovirus
Xenotransplantation, 2015AbstractPorcine microorganisms may be transmitted to the human recipient when xenotransplantation with pig cells, tissues, and organs will be performed. Most of such microorganisms can be eliminated from the donor pig by specified or designated pathogen‐free production of the animals.
Joachim Denner
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Journal of Virological Methods, 2007
The use of porcine organs is being developed as a means to alleviate the shortage of human organs for transplantation. Recommendations have been published for the microbiological specifications of organ-source pigs to reduce the possibility of a microorganism from pigs being inadvertently transferred to the recipient of the xenograft.
Chul-Seung, Lee +6 more
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The use of porcine organs is being developed as a means to alleviate the shortage of human organs for transplantation. Recommendations have been published for the microbiological specifications of organ-source pigs to reduce the possibility of a microorganism from pigs being inadvertently transferred to the recipient of the xenograft.
Chul-Seung, Lee +6 more
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Xenotransplantation, 2016
AbstractBackgroundTo prevent transmission of zoonotic microorganisms from pig transplants to human recipients when performing xenotransplantation using pig cells, tissues, or organs, donor pigs have to be carefully characterized. Göttingen minipigs (GöMP) are often used for various biomedical investigations and are well characterized concerning the ...
Vladimir A, Morozov +4 more
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AbstractBackgroundTo prevent transmission of zoonotic microorganisms from pig transplants to human recipients when performing xenotransplantation using pig cells, tissues, or organs, donor pigs have to be carefully characterized. Göttingen minipigs (GöMP) are often used for various biomedical investigations and are well characterized concerning the ...
Vladimir A, Morozov +4 more
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The porcine cytomegalovirus (PCMV) will not stop xenotransplantation
Xenotransplantation, 2022Joachim Denner
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Porcine cytomegalovirus (PCMV) in early gestation
Veterinary Microbiology, 1988Following intranasal exposure to PCMV at or within 48 h of coitus transplacental infection occurred in two groups of gilts. Five out of 22 embryos were infected in the first group but only 2 out of 63 in the second. A more rapid immune response as measured by circulating antibody was probably instrumental in abrogating infection in the second group. In
N, Edington, A E, Wrathall, J T, Done
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Isolation and Experimental Infection with Porcine Cytomegalovirus
Zentralblatt für Veterinärmedizin Reihe B, 1977SummaryFive strains of porcine cytomegalovirus (PCMV) were isolated in cultures of pig lung macrophages (PLM) from pigs aged about 3 weeks. Two of them were isolated from the nasal mucosa and the remaining three from the lung. The presence of PCMV in PLM cultures was demonstrated indirectly by staining and directly by electron microscopy.
L, Valícek, B, Smíd, J, Mensík
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Superinfection with porcine cytomegalovirus initiating transplacental infection
Veterinary Microbiology, 1988Four sows with circulating antibody were exposed to porcine cytomegalovirus. Virus was detected in 8 of 24 foetuses by immunofluorescence and/or virus isolation from 2 sows with low levels of antibody. In 6 of the infected foetuses, the virus was in capillary endothelium and macrophages of the lung, and was associated with interlobular oedema in 2 of ...
N, Edington +3 more
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