Results 161 to 170 of about 13,344 (185)

Human Fibroblasts Are Permissive for Porcine Cytomegalovirus In Vitro

Transplantation, 2008
Xenotransplantation with pig organs is being considered to alleviate donor organ shortages; however, the risk of introducing porcine viruses into humans is heightened in this setting. The goal of this study was to determine the infectious potential of porcine cytomegalovirus (PCMV), a xenozoonotic virus of interest, in human fibroblasts in vitro ...
Jennifer L, Whitteker, Anil K, Dudani, Eilleen S, Tackaberry   +2 more
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HUMAN CYTOMEGALOVIRUS PRODUCTIVELY INFECTS PORCINE ENDOTHELIAL CELLS IN VITRO

Transplantation, 2001
The possibility that human cytomegalovirus (HCMV) may infect porcine endothelial cells (ECs) was investigated. This may be relevant during xenotransplantation of porcine cells or organs into human recipients.HCMV was inoculated into low-passage porcine ECs.
M, Degré, T, Ranneberg-Nilsen, S, Beck, H, Rollag, A E, Fiane   +4 more
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Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation.

Transplantation, 2003
A rapidly progressive disorder termed consumptive coagulopathy (CC) has been observed frequently in pig-to-baboon renal xenotransplantation. CC may be initiated by endothelial activation and induction of procoagulant factors after immunologic injury or infection, or by molecular incompatibilities between porcine coagulation proteins and primate ...
Gollackner, Bernd, Mueller, Nicolas J, Houser, Stuart, Qawi, Imrana, Soizic, Daniel, Knosalla, Christoph, Buehler, Leo Hans, Dor, Frank J M F, Awwad, Michel, Sachs, David H, Cooper, David K C, Robson, Simon C, Fishman, Jay A   +12 more
openaire   +4 more sources

Electron Microscopy of Porcine Cytomegalovirus in Pig Lung Macrophage Cultures

Zentralblatt für Veterinärmedizin Reihe B, 2010
Summary Two strains of porcine cytomegalovirus (PCMV), strain B 4 and the reference strain ADRI-1, were studied in culture of pig lung macrophages (PLM) by electron microscopy. The nuclei of PLM contained various forms of nucleocapsids of differing core structure.
L, Valícek, B, Smíd
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Porcine Cytomegalovirus (PCMV)

1989
Cytomegalovirus infections are very common in many species (1,2,3,4,5). They induce host specific cytomegalic intranuclear inclusions in various organs. PCMV was first identified as inclusion body rhinitis (IBR) of pigs in Great Britain by Done and coworkers in 1955 (6). Obviously PCMV is inapparently present in most pig herds and causes generally mild
openaire   +1 more source

Reduction of Consumptive Coagulopathy Using Porcine Cytomegalovirus-Free Cardiac Porcine Grafts in Pig-to-Primate Xenotransplantation

Transplantation, 2004
Xenotransplantation using pigs as the source species for organs carries a potential risk for transmission and activation of porcine herpesviruses. Activation of porcine cytomegalovirus (PCMV) in pig-to-baboon xenotransplantation is associated with xenograft injury and possibly an increased incidence of consumptive coagulopathy (CC).To further ...
Nicolas J, Mueller, Kenji, Kuwaki, Frank J M F, Dor, Christoph, Knosalla, Bernd, Gollackner, Robert A, Wilkinson, David H, Sachs, David K C, Cooper, Jay A, Fishman   +8 more
openaire   +2 more sources

In situ hybridization and immunohistochemistry for the detection of porcine cytomegalovirus

Journal of Virological Methods, 2012
To establish in situ hybridization and immunohistochemistry based-assays for the detection of porcine cytomegalovirus, routinely processed renal tissue sections from 34 diseased piglets suspected of having the infection were obtained and examined. Using hematoxylin and eosin, porcine cytomegalovirus inclusion bodies were found in the nucleus of renal ...
Maki, Sekiguchi, Tomoyuki, Shibahara, Ayako, Miyazaki, Tomoko, Tajima, Shinya, Shimizu, Emmanuel, Kabali, Yoshiyuki, Takano, Yosuke, Sasaki, Masanori, Kubo   +8 more
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Electron microscopy of porcine cytomegalovirus

Archiv für die gesamte Virusforschung, 1973
Porcine cytomegalovirus was examined by electron microscopy in the nasal mucosa of piglets from a natural epizootic of the disease with the object to determine the localization of nucleocapsids arranged in crystalline arrays in the cell and to investigate the structure of most common viral forms. The study revealed the following. 1.
L, Valícek, B, Smíd, J, Mensík
openaire   +2 more sources

Early testing of porcine organ xenotransplantation products in humans: Microbial safety as illustrated for porcine cytomegalovirus

Xenotransplantation, 2022
Joachim Denner, Henk‐Jan Schuurman
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Monitoring of porcine and baboon cytomegalovirus infection in xenotransplantation

Xenotransplantation, 2009
Mueller, N J, Ezzelarab, M, Buhler, L, Haeberli, L, Ayares, D, Cooper, D K   +5 more
openaire   +2 more sources