Porcine cytomegalovirus - Open Access .click

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Reduction of Consumptive Coagulopathy Using Porcine Cytomegalovirus-Free Cardiac Porcine Grafts in Pig-to-Primate Xenotransplantation

Transplantation, 2004
Xenotransplantation using pigs as the source species for organs carries a potential risk for transmission and activation of porcine herpesviruses. Activation of porcine cytomegalovirus (PCMV) in pig-to-baboon xenotransplantation is associated with xenograft injury and possibly an increased incidence of consumptive coagulopathy (CC).To further ...
Nicolas J, Mueller +8 more
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Primary human fibroblasts are permissive for porcine cytomegalovirus in vitro

2013
Xenotransplantation with pig organs is being considered to alleviate donor organ shortages; however, the risk of introducing porcine viruses to humans is exaggerated in this setting. Accordingly, the goal of this study was to determine the infectious potential of porcine cytomegalovirus (PCMV), a xenozoonotic virus of interest, in human fibroblasts in ...
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Early testing of porcine organ xenotransplantation products in humans: Microbial safety as illustrated for porcine cytomegalovirus

Xenotransplantation, 2022
Joachim Denner, Henk‐Jan Schuurman
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Monitoring of porcine and baboon cytomegalovirus infection in xenotransplantation