Results 21 to 30 of about 7,014 (162)

One-Tube Nested Real-Time PCR Assay for Rapid Screening of Porcine Cytomegalovirus in Clinical Samples [PDF]

Frontiers in Veterinary Science, 2020
Porcine cytomegalovirus (PCMV) is a pathogen that must be removed from pigs for use as organ donors in xenotransplantation. Recently, it has been found that when donor pigs are infected with PCMV, a pig-to-non-human-primate xenotransplantation lower ...
Hye-young Wang, Joong Ki Song, Seongho Shin, Ki Myung Choi, Hyunil Kim   +4 more
doaj   +2 more sources

Susceptibility of porcine cytomegalovirus to antiviral drugs [PDF]

Journal of Antimicrobial Chemotherapy, 2004
Re-activation of porcine cytomegalovirus (PCMV) in the xenograft has been reported in pig-to-baboon models of xenotransplantation and is associated with invasive disease and consumptive coagulopathy. If xenotransplantation of porcine organs into human recipients is to proceed, donor organs will have to be free from a wide range of infectious agents ...
Jacqueline F L, Fryer, Paul D, Griffiths, Vincent C, Emery, Duncan A, Clark   +3 more
openaire   +3 more sources

Detection of porcine cytomegalovirus, a roseolovirus, in pig ovaries and follicular fluid: implications for somatic cells nuclear transfer, cloning and xenotransplantation [PDF]

Virology Journal, 2023
Background Porcine cytomegalovirus (PCMV) is a porcine roseolovirus (PCMV/PRV) which is widely distributed in pigs. Transmission of PCMV/PRV in preclinical xenotransplantations was shown to significantly reduce the survival time of the pig transplants in
Sabrina Hansen, Konrad Fischer, Ludwig Krabben, Alexander Rinke Carrapeiro, Bernhard Klinger, Angelika Schnieke, Benedikt Kaufer, Joachim Denner   +7 more
doaj   +2 more sources

Activation of Porcine Cytomegalovirus, but Not Porcine Lymphotropic Herpesvirus, in Pig‐to‐Baboon Xenotransplantation [PDF]

The Journal of Infectious Diseases, 2004
Tissue-invasive disease due to porcine cytomegalovirus (PCMV) has been demonstrated after pig-to-baboon solid-organ xenotransplantation. Porcine lymphotropic herpesvirus (PLHV)-1 is associated with B cell proliferation and posttransplant lymphoproliferative disorder after allogeneic bone marrow transplantation in swine but has not been observed in pig ...
Mueller, Nicolas J, Livingston, Christine, Knosalla, Christoph, Barth, Rolf N, Yamamoto, Shin, Gollackner, Bernd, Dor, Frank J M F, Buehler, Leo Hans, Sachs, David H, Yamada, Kazuhiko, Cooper, David K C, Fishman, Jay A   +11 more
openaire   +3 more sources

Quantitation of Porcine Cytomegalovirus in Pig Tissues by PCR [PDF]

Journal of Clinical Microbiology, 2001
ABSTRACT A quantitative-competitive PCR for the quantification of porcine cytomegalovirus (PCMV) was developed. The virus was detected in a variety of pig organs (including potential xenotransplant donations), with viral loads ranging from <10 to 97 genome copies/μg of DNA.
Fryer, J. F. L., Griffiths, P. D., Fishman, Jay, Emery, V. C., Clark, D. A.   +4 more
openaire   +5 more sources

Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig‐to‐baboon renal xenotransplantation in vivo [PDF]

Xenotransplantation, 2018
AbstractBackgroundStudies of xenotransplantation from swine have identified porcine viruses as potential barriers to clinical trials. The biology of these viruses has not been extensively investigated in the in vivo xeno‐environment. Enhancement of viral gene expression by viral and cellular factors acting intranshas been demonstrated for certain ...
Jay A Fishman, David H Sachs, Kazuhiko Yamada   +2 more
exaly   +5 more sources

Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation.

Transplantation, 2003
A rapidly progressive disorder termed consumptive coagulopathy (CC) has been observed frequently in pig-to-baboon renal xenotransplantation. CC may be initiated by endothelial activation and induction of procoagulant factors after immunologic injury or infection, or by molecular incompatibilities between porcine coagulation proteins and primate ...
Gollackner, Bernd, Mueller, Nicolas J, Houser, Stuart, Qawi, Imrana, Soizic, Daniel, Knosalla, Christoph, Buehler, Leo Hans, Dor, Frank J M F, Awwad, Michel, Sachs, David H, Cooper, David K C, Robson, Simon C, Fishman, Jay A   +12 more
core   +4 more sources

Role of a Porcine Herpesvirus, PCMV/PRV, in Xenotransplantation [PDF]

Transplant International
Xenotransplantation using pig organs may be associated with the transmission of porcine viruses that could cause disease in recipients. A well-known example is the porcine cytomegalovirus, which is actually a porcine roseolovirus, hence abbreviated as ...
Joachim Denner
doaj   +4 more sources

Porcine cytomegalovirus: A very unwelcome stowaway. [PDF]

Xenotransplantation, 2022
Mueller NJ.
europepmc   +4 more sources

Clinical cystoisosporosis associated to porcine cytomegalovirus (PCMV, Suid herpesvirus 2) infection in fattening pigs. [PDF]

Parasitol Int, 2017
Cystoisospora (syn. Isospora) suis is the causative agent of neonatal porcine coccidiosis and one of the main causes of diarrhoea in suckling piglets worldwide.
Basso W, Marti H, Hilbe M, Sydler T, Stahel A, Bürgi E, Sidler X.   +6 more
europepmc   +2 more sources