Results 31 to 40 of about 7,014 (162)
Primary human fibroblasts are permissive for porcine cytomegalovirus in vitro
, 2013 Xenotransplantation with pig organs is being considered to alleviate donor organ shortages; however, the risk of introducing porcine viruses to humans is exaggerated in this setting. Accordingly, the goal of this study was to determine the infectious potential of porcine cytomegalovirus (PCMV), a xenozoonotic virus of interest, in human fibroblasts in ...
Whitteker, Jennifer L
openaire +3 more sources
Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation
Viruses, 2021 Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases
Joachim Denner
doaj +1 more source
Regulation of antiviral and antimicrobial innate immunity and immune evasion [PDF]
Cellular and Molecular Life SciencesThe interplay between host innate immunity and pathogen evasion is a dynamic battle shaping infection outcomes. The Topical Collection “Regulation of Antiviral and Antimicrobial Innate Immunity and Immune Evasion” synthesizes findings from thirteen ...
Ling Wang +4 more
doaj +2 more sources
Virus Safety of Xenotransplantation
Viruses, 2022 The practice of xenotransplantation using pig islet cells or organs is under development to alleviate the shortage of human donor islet cells or organs for the treatment of diabetes or organ failure.
Joachim Denner
doaj +1 more source
Virological Characterization of Pigs with Erythema Multiforme
Microorganisms, 2022 Erythema multiforme in pigs is an acute, self-limiting disease characterized by red skin areas and often associated with anorexia, fever and respiratory problems. The cause of the disease remains unknown.
Sabrina Halecker +5 more
doaj +1 more source
Experimental transplacental transmission of porcine cytomegalovirus [PDF]
Journal of Hygiene, 1977 SUMMARYSix serologically negative sows were infected by intranasal instillation of porcine cytomegalovirus (PCMV) between 31 and 85 days of pregnancy. Four sows showed an afebrile anorexia and lethargy 14–25 days after infection and all 6 developed significant increases in indirect immunofluorescent (IIF) antibody titres within 35 days.
N. Edington +4 more
openaire +2 more sources
PCR Assay for Detecting Porcine Cytomegalovirus [PDF]
Journal of Clinical Microbiology, 1999 ABSTRACT This is the first published report of a PCR assay for detecting porcine cytomegalovirus (PCMV), the causative agent of inclusion body rhinitis in pigs. The DNA to be tested was extracted directly from lungs and nasal scrapings of pigs with various clinical syndromes. Fifty-nine percent (74 of 126) of tested pigs with various clinical
A L, Hamel +4 more
openaire +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Xenotransplantation, EarlyView., 2020 Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Reactivation of Porcine Cytomegalovirus through Allogeneic Stimulation [PDF]
Journal of Clinical Microbiology, 2004 ABSTRACT Reactivation of latent porcine cytomegalovirus after coculture of peripheral blood mononuclear cells (PBMCs) from pigs with different genetic backgrounds was investigated. Nine of 10 allogeneic coculture pairs were PCR (DNA) positive, whereas 7 coculture pairs had porcine cytomegalovirus (PCMV) RNA, an indication of ...
Maria Isabel M C, Guedes +3 more
openaire +2 more sources