Results 31 to 40 of about 13,344 (185)

Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation

Viruses, 2021
Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases
Joachim Denner
doaj   +1 more source

Varicellovirus UL 49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP [PDF]

, 2008
Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides, presented in the context of MHC class I molecules at the surface of the infected cell.
Bienkowska-Szewczyk, Krystyna, Chowdhury, Shafiqul I., Daus, Franz, Heemskerk, Mirjam H. M., Koch, Joachim, Koppers-Lalic, Danijela, Lipinska, Andrea D., Loch, Sandra, Marcondes Rezende, Marisa, Mettenleiter, Thomas C., Neefjes, Jacques J., Osterrieder, Nikolaus, Quinten, Edwin, Reits, Eric A., Ressing, Maaike E., Rijsewijk, Frans A. M., Tampé, Robert, Verweij, Marieke C., Wang, Ying, Wiertz, Emmanuel J. H. J.   +19 more
core   +12 more sources

Virus Safety of Xenotransplantation

Viruses, 2022
The practice of xenotransplantation using pig islet cells or organs is under development to alleviate the shortage of human donor islet cells or organs for the treatment of diabetes or organ failure.
Joachim Denner
doaj   +1 more source

Experimental transplacental transmission of porcine cytomegalovirus [PDF]

Journal of Hygiene, 1977
SUMMARYSix serologically negative sows were infected by intranasal instillation of porcine cytomegalovirus (PCMV) between 31 and 85 days of pregnancy. Four sows showed an afebrile anorexia and lethargy 14–25 days after infection and all 6 developed significant increases in indirect immunofluorescent (IIF) antibody titres within 35 days.
N. Edington, R. G. Watt, W. Plowrights, A. E. Wrathall, J. T. Done   +4 more
openaire   +2 more sources

PCR Assay for Detecting Porcine Cytomegalovirus [PDF]

Journal of Clinical Microbiology, 1999
ABSTRACT This is the first published report of a PCR assay for detecting porcine cytomegalovirus (PCMV), the causative agent of inclusion body rhinitis in pigs. The DNA to be tested was extracted directly from lungs and nasal scrapings of pigs with various clinical syndromes. Fifty-nine percent (74 of 126) of tested pigs with various clinical
A L, Hamel, L, Lin, C, Sachvie, E, Grudeski, G P, Nayar   +4 more
openaire   +2 more sources

Virological Characterization of Pigs with Erythema Multiforme

Microorganisms, 2022
Erythema multiforme in pigs is an acute, self-limiting disease characterized by red skin areas and often associated with anorexia, fever and respiratory problems. The cause of the disease remains unknown.
Sabrina Halecker, Vasileios Papatsiros, Dimitra Psalla, Ludwig Krabben, Benedikt Kaufer, Joachim Denner   +5 more
doaj   +1 more source

Reactivation of Porcine Cytomegalovirus through Allogeneic Stimulation [PDF]

Journal of Clinical Microbiology, 2004
ABSTRACT Reactivation of latent porcine cytomegalovirus after coculture of peripheral blood mononuclear cells (PBMCs) from pigs with different genetic backgrounds was investigated. Nine of 10 allogeneic coculture pairs were PCR (DNA) positive, whereas 7 coculture pairs had porcine cytomegalovirus (PCMV) RNA, an indication of ...
Maria Isabel M C, Guedes, Jack M, Risdahl, Barry, Wiseman, Thomas W, Molitor   +3 more
openaire   +2 more sources

Susceptibility of porcine cytomegalovirus to antiviral drugs [PDF]

Journal of Antimicrobial Chemotherapy, 2004
Re-activation of porcine cytomegalovirus (PCMV) in the xenograft has been reported in pig-to-baboon models of xenotransplantation and is associated with invasive disease and consumptive coagulopathy. If xenotransplantation of porcine organs into human recipients is to proceed, donor organs will have to be free from a wide range of infectious agents ...
Jacqueline F L, Fryer, Paul D, Griffiths, Vincent C, Emery, Duncan A, Clark   +3 more
openaire   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Cellular xenotransplantation of animal cells into people: benefits and risk [PDF]

, 2018
The main benefit of xenotransplantation is its potential to overcome the worldwide organ shortage experienced in allotransplantation. Allogeneic transplantation is the only successful therapy for several life-threatening diseases, with cell, tissue or ...
Cozzi, Emanuele, Galli, Cesare, Gianello, Pierre, Schuurman, H.-J., Scobie, Linda   +4 more
core   +1 more source