Results 31 to 40 of about 148,131 (169)

Susceptibility of porcine cytomegalovirus to antiviral drugs [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2004
Re-activation of porcine cytomegalovirus (PCMV) in the xenograft has been reported in pig-to-baboon models of xenotransplantation and is associated with invasive disease and consumptive coagulopathy. If xenotransplantation of porcine organs into human recipients is to proceed, donor organs will have to be free from a wide range of infectious agents ...
Jacqueline F L, Fryer   +3 more
openaire   +2 more sources

Activation of Porcine Cytomegalovirus, but Not Porcine Lymphotropic Herpesvirus, in Pig‐to‐Baboon Xenotransplantation [PDF]

open access: yesThe Journal of Infectious Diseases, 2004
Tissue-invasive disease due to porcine cytomegalovirus (PCMV) has been demonstrated after pig-to-baboon solid-organ xenotransplantation. Porcine lymphotropic herpesvirus (PLHV)-1 is associated with B cell proliferation and posttransplant lymphoproliferative disorder after allogeneic bone marrow transplantation in swine but has not been observed in pig ...
Mueller, Nicolas J   +11 more
openaire   +2 more sources

Quantitation of Porcine Cytomegalovirus in Pig Tissues by PCR [PDF]

open access: yesJournal of Clinical Microbiology, 2001
ABSTRACT A quantitative-competitive PCR for the quantification of porcine cytomegalovirus (PCMV) was developed. The virus was detected in a variety of pig organs (including potential xenotransplant donations), with viral loads ranging from <10 to 97 genome copies/μg of DNA.
Fryer, J. F. L.   +4 more
openaire   +4 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Report from the second cytomegalovirus and immunosenescence workshop. [PDF]

open access: yes, 2011
The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory frequency, inflation and immunosenescence;
Pawelec, Graham   +328 more
core   +3 more sources

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Studies on the Morphogenesis of Murine Cytomegalovirus [PDF]

open access: yes, 1986
Two modes of assembly of murine cytomegalovirus (MCMV) were observed in cultured mouse embryo fïbroblasts, generating two morphologically different types of viral particles: monocapsid virions and multicapsid virions.
Reddehase, M. J.   +9 more
core   +1 more source

Reactivation of Porcine Cytomegalovirus through Allogeneic Stimulation [PDF]

open access: yesJournal of Clinical Microbiology, 2004
ABSTRACT Reactivation of latent porcine cytomegalovirus after coculture of peripheral blood mononuclear cells (PBMCs) from pigs with different genetic backgrounds was investigated. Nine of 10 allogeneic coculture pairs were PCR (DNA) positive, whereas 7 coculture pairs had porcine cytomegalovirus (PCMV) RNA, an indication of ...
Maria Isabel M C, Guedes   +3 more
openaire   +2 more sources

Sequential anti-cytomegalovirus response monitoring may allow prediction of cytomegalovirus reactivation after allogeneic stem cell transplantation [PDF]

open access: yes, 2012
Background: Reconstitution of cytomegalovirus-specific CD3+CD8+ T cells (CMV-CTLs) after allogeneic hematopoietic stem cell transplantation (HSCT) is necessary to bring cytomegalovirus (CMV) reactivation under control. However, the parameters determining
Matthias Eder (21135)   +56 more
core   +2 more sources

The porcine virome and xenotransplantation

open access: yesVirology Journal, 2017
The composition of the porcine virome includes viruses that infect pig cells, ancient virus-derived elements including endogenous retroviruses inserted in the pig chromosomes, and bacteriophages that infect a broad array of bacteria that inhabit pigs ...
Joachim Denner
doaj   +1 more source

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