Results 71 to 80 of about 7,014 (162)
Organoids: From Bench to Bedside Applications
MedComm, Volume 7, Issue 6, June 2026.Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
MedComm, Volume 7, Issue 6, June 2026.A bioartificial liver (BAL) integrating GGTA1‐knockout porcine hepatocytes and R‐spondin1‐overexpressing endothelial organoids was tested using plasma from patients with acute‐on‐chronic liver failure (ACLF). The BAL system actively modulates amino acid and lipid metabolism, enhances detoxification, partially restores overall metabolic balance, and ...
Yuting He +8 more
wiley +1 more source
Current Status of Kidney Xenotransplantation in Basic Research
Organ Medicine, Volume 3, Issue 2, Page 87-101, June 2026.Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley +1 more source
Microbial Biotechnology, Volume 19, Issue 6, June 2026.By displaying the hemagglutinin (HA) or neuraminidase (NA) proteins of influenza viruses on the surface of baculoviruses and infected insect cells, a safe and flexible pseudovirus system capable of performing cytokine analysis, serological detection and antiviral drug screening is established.
Li‐Yun Cheng +7 more
wiley +1 more source
Australian porcine circoviruses
, 2006 Two types of porcine circovirus (PCV) exist, referred to as PCV1 and PCV2. PCV2 has been associated with disease syndromes in pigs, including that designated postweaning multisystemic wasting syndrome (PMWS), which has been identified in all regions of ...
Muhling, Jill
core
Studies on porcine cytomegalovirus relevant to xenotransplantation. [PDF]
, 2005 Xenotransplantation of porcine organs into humans provides a potential solution to the current shortage of human donor organs, but raises considerable safety concerns including the potential transmission of porcine infectious agents, particularly viruses,
Fryer, J.F.L.
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Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease
Immunology, Volume 178, Issue 2, Page 218-230, June 2026.This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley +1 more source
Effect of Immunosuppressive Treatment on Porcine Cytomegalovirus Infection
, 2002 Guedes, Maria; Risdahl, Jack; Wiseman, Barry; Molitor, Thomas. (2002). Effect of Immunosuppressive Treatment on Porcine Cytomegalovirus Infection.
Risdahl, Jack +3 more
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Potential Infectious Complications in Pig Xenograft Donors and Recipients
Transplant InternationalPreclinical and clinical xenotransplantation trials have shown that successful outcomes depend on a number of factors including the prevention of xenozoonoses.
Nicolas J. Mueller, Linda Scobie
doaj +1 more source
Methods for Studying Endocytotic Pathways of Herpesvirus Encoded G Protein-Coupled Receptors
Molecules, 2020 Endocytosis is a fundamental process involved in trafficking of various extracellular and transmembrane molecules from the cell surface to its interior. This enables cells to communicate and respond to external environments, maintain cellular homeostasis,
Maša Mavri +5 more
doaj +1 more source