Xenotransplantation from pig to humans may be associated with the risk of transmission of porcine endogenous retroviruses (PERVs) that are present in the genome of all pigs and that infect human cells in vitro. However, it remains unclear whether PERVs infect transplant recipients in vivo and, if so, whether they are pathogenic.
Joachim, Denner +7 more
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Methods and Tools for Detection and Evaluation of the Risks of Porcine Endogenous Retrovirus in Porcine to Human Xenotransplantation [PDF]
Carolyn A. Wilson, Takele Argaw
core +1 more source
The prevention strategies of swine viruses related to xenotransplantation. [PDF]
Mao H +5 more
europepmc +1 more source
Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor. [PDF]
Zheng S +11 more
europepmc +1 more source
Characterization of porcine endogenous retrovirus insertion in Jeju native pigs and commercial breeds. [PDF]
Yoon S +9 more
europepmc +1 more source
Revolutionizing medicine: Exploring the breakthroughs in liver xenotransplantation. [PDF]
El-Kassas M, Abdelhamed W, Al-Naamani K.
europepmc +1 more source
Xeno kidney: revolutionizing kidney disease treatment. [PDF]
Makkar D, Gakhar D, Rakha A.
europepmc +1 more source
Cardiac Xenotransplantation: a New Frontier for Advanced Heart Failure. [PDF]
Montgomery RA, Tang WHW.
europepmc +1 more source
Xenotransplantation may develop into a medical technology able to save or improve the quality of life. Porcine endogenous retroviruses (PERVs), because they are integrated in the genome of all pig strains, because they are produced by normal pig cells, and because they can infect human cell in vitro, are considered to be the main microbiological risk ...
openaire +1 more source
Further Evidence for the Immunosuppressive Activity of Transmembrane Envelope Protein p15E of Porcine Endogenous Retrovirus. [PDF]
Denner J +6 more
europepmc +1 more source

