Results 71 to 80 of about 2,630 (176)

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, Volume 5, Issue 4, August 2025.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

CaribVET, le réseau caribéen de santé animale [PDF]

, 2011
Le Réseau caribéen de santé animale CaribVET a été créé en l'an 2000 afin de contribuer au renforcement et à l'harmonisation de la surveillance et du contrôle des maladies animales transfrontalières pour améliorer la situation sanitaire et la ...
Bournez, Laure, Gongora, Victor, Kalloo, Margaret, Lefrançois, Thierry, Petit Sinturel, Marion, Pradel, Jennifer, Shaw, John, Vachiery, Nathalie   +7 more
core  

Construction and characterization of the full-length cDNA of an infectious clone of emerging porcine teschovirus-2

Pathogens and Disease, 2022
Abstract Porcine teschovirus (PTV) is a causative agent of polioencephalomyelitis, encephalomyelitis, reproductive disorders and gastrointestinal and respiratory diseases in swine. In the present study, the PTV2 GX/2020 strain was isolated from pig intestinal tissue through the use of ST cells.
Yuying Li, Shengnan Chen, Yaokai Shi, Haixin Huang, Wei Wang, Min Zheng, Chenchen Zhao, Xinyu Zhang, Xiaoxiao Lei, Wenchao Sun, Hao Liu, Tian Lan   +11 more
openaire   +2 more sources

A game of tag: A review of protein tags for the successful detection, purification and fluorescence labelling of proteins expressed in microalgae

The Plant Journal, Volume 122, Issue 6, June 2025.
Significance Statement Protein tags for detection, purification and fluorescence labelling are vital in microalgal research, yet the suitability of specific tags remains largely unexplored. This review discusses the pros and cons of a comprehensive list of protein tags and provides important guidance for experimental design within a microalgal context.
Jonathan Scarfe, Darius Kosmützky, R. Ellen R. Nisbet   +2 more
wiley   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Advanced Science, Volume 12, Issue 18, May 15, 2025.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang   +21 more
wiley   +1 more source

Risk analysis tool developed to assist with decision-making on prevention of swine diseases. Application to Porcine Epidemic Diarrhea in Caribbean countries. [P029] [PDF]

, 2015
Purpose Classical Swine Fever (CSF) and Teschovirus Encephalomyelitis (TE) have been identified as priority diseases for the Caribbean because of their sanitary, economic and social repercussions in affected countries, together with their high diffusion ...
Calvo, Francisco, Casal, Jordi, Casals, Maria alba, Ellis, G., Frias Lepoureau, Maria Teresa, Gongora, Victor, Guitian, Javier, Percedo Abreu, M.I., Pradel, Jennifer, Zepeda, C.M.   +9 more
core  

Longitudinal Investigation of Brain and Spinal Cord Pericytes After Inducible PDGFRβ+ Cell Ablation in Adult Mice

Journal of Neurochemistry, Volume 169, Issue 3, March 2025.
Pericytes are essential for central nervous system vascular function, yet studying their role in adult pathologies has been challenging due to the scarcity of well‐characterized models that preserve normal vascular development. A tamoxifen‐inducible pericyte ablation model was developed to investigate pericyte dynamics after the acute loss of pericytes.
Dila Atak, Erdost Yıldız, Esra Özkan, Mohammadreza Yousefi, Ayşe Özkan, Aysu Bilge Yılmaz, Ali Burak Kızılırmak, Iman Asaad Alnajjar, Çiçek Kanar, Zeynep Lal Caan, Şakir Ümit Zeybek, Cem İsmail Küçükali, Erdem Tüzün, Yasemin Gürsoy‐Özdemir, Atay Vural   +14 more
wiley   +1 more source

Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells [PDF]

, 2017
The expression of p63 in surface ectodermal cells during development of the cornea, skin, oral mucosa and olfactory placodes is integral to the process of cellular self-renewal and the maintenance of the epithelial stem cell status.
Hayashi, R., Kobayashi, Y., Nishida, K., Quantock, Andrew J.   +3 more
core   +3 more sources

A Piglet with Concurrent Polioencephalomyelitis due to Porcine Teschovirus and Postweaning Multisystemic Wasting Syndrome

Journal of Veterinary Medical Science, 2008
A piglet developed respiratory distress followed by difficulty in standing and unsteady gait. The lesions were characterized by polioencephalomyelitis with the predominant distribution in the brain stem, as well as lymphocyte depletion and histiocyte infiltration with cytoplasmic inclusion bodies in the lymphoid tissues throughout the body and ...
Maki, Takahashi, Yukio M, Seimiya, Yoshihisa, Seki, Manabu, Yamada   +3 more
openaire   +3 more sources

Biomimetic Triplet Messenger RNA Formulation in MXene Hydrogel Microneedles for Wound Healing

Aggregate, Volume 6, Issue 2, February 2025.
The current direction in the messenger RNA (mRNA) field is focused on imparting mRNA with competitive synthetic functions and delicating carrier systems. By leveraging advanced artificial intelligence technology, a novel triplet mRNA formulation has been developed and delivered via photothermal‐responsive microneedles for the treatment of diabetic ...
Ji Wang, Yu Wang, Minhui Lu, Xinyue Cao, Ming Xia, Miaoqing Zhao, Yuanjin Zhao   +6 more
wiley   +1 more source