Results 81 to 90 of about 2,630 (176)
mLife, Volume 4, Issue 1, Page 55-69, February 2025.Abstract The global dissemination of H5 avian influenza viruses represents a significant threat to both human and animal health. In this study, we conducted a genome‐wide siRNA library screening against the highly pathogenic H5N1 influenza virus, leading us to the identification of 457 cellular cofactors (441 proviral factors and 16 antiviral factors ...
Guangwen Wang +15 more
wiley +1 more source
Influence of brain-derived neurotrophic factor on pathfinding of dentate granule cell axons, the hippocampal mossy fibers [PDF]
, 2009 Mossy fibers, the dentate granule cell axons, are generated throughout an animal's lifetime. Mossy fiber paths and synapses are primarily restricted to the stratum lucidum within the CA3 region.
Makoto Tamura +6 more
core +2 more sources
Transboundary and Emerging Diseases, Volume 2025, Issue 1, 2025.Seneca Valley virus (SVV) infection has recently disseminated across pig farms in Canada, America, and China. The SVV has been identified in humans, rodents, and houseflies. Although cross‐species transmission events may lead to limited subsequent transmission, sustained outbreaks have been observed in new mammalian hosts.
Ziliang Qin +14 more
wiley +1 more source
Neuropathology and diagnostics in food animals [PDF]
, 2012 Diseases of the central nervous system are relatively common in food animals. Potential causes include infectious agents, nutritional deficiencies, metabolic disorders, genetic defects, toxins, and idiopathic causes. Food animals are frequently raised in
Nietfeld, Jerome C.
core +1 more source
Identification of Novel Rosavirus Species That Infects Diverse Rodent Species and Causes Multisystemic Dissemination in Mouse Model [PDF]
, 2016 published_or_final_versio
Chan, BC +12 more
core +1 more source
Human enterovirus 71 and hand, foot and mouth disease [PDF]
, 2010 Hand, foot and mouth disease (HFMD) is generally a benign febrile exanthematous childhood disease caused by human enteroviruses. The route of transmission is postulated to be faeco-oral in developing areas but attributed more to respiratory droplet in ...
Lau, SKP, Wong, SSY, Yip, CCY, Yuen, KY
core +1 more source
Journal of General Virology, 2018 Porcine teschovirus (PTV) comprises at least 13 genotypes (PTV 1-13). Here, the genotypes of field strains prevalent among pig populations in Hunan Province, China, were identified. Multiple PTV genotypes, including all genotypes except PTV 7 and 8, were found co-circulating in the pig populations, reflecting a high genetic diversity.
Taotao, Yang +6 more
openaire +2 more sources
Blastocyst complementation generates exogenous donor‐derived liver in ahepatic pigs
The FASEB Journal, Volume 38, Issue 21, 15 November 2024.We report for the first time the generation of gut‐specific knockout of HHEX required for hepatogenesis and rescued the mutants by chimerism. Key highlights are below: Generated a gut‐specific CRE driver in a pig model. Generated and characterized the conditional knockout of HHEX required for hepatogenesis.
Sean G. Simpson +7 more
wiley +1 more source
Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis [PDF]
, 2017 Genetic alterations conferring resistance to the effects of chemical inhibitors are valuable tools for validating on-target effects in cells. Unfortunately, for many therapeutic targets such alleles are not available.
Arai, E. +7 more
core +1 more source
FGF8 coordinates tissue elongation and cell epithelialization during early kidney tubulogenesis. [PDF]
, 2015 胚成長と連動する管組織形成メカニズムの解明 －臓器不全治療や再生医療に期待－. 京都大学プレスリリース. 2015-07-03.When a tubular structure forms during early embryogenesis, tubular elongation and lumen formation (epithelialization) proceed simultaneously in a spatiotemporally coordinated manner. We here
Atsuta, Yuji, Takahashi, Yoshiko
core +3 more sources