Cell entry mechanism of enzymatic bacterial colicins: Porin recruitment and the thermodynamics of receptor binding [PDF]
, 2005 Binding of enzymatic E colicins to the vitamin B-12 receptor, BtuB, is the first stage in a cascade of events that culminate in the translocation of the cytotoxic nuclease into the Escherichia coli cytoplasm and release of its tightly bound immunity ...
Housden, Nicholas G. +4 more
core +3 more sources
Small, EarlyView.Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi +13 more
wiley +1 more source
Anti-infectives in Drug Delivery-Overcoming the Gram-Negative Bacterial Cell Envelope. [PDF]
, 2017 Infectious diseases are becoming a major menace to the state of health worldwide, with difficulties in effective treatment especially of nosocomial infections caused by Gram-negative bacteria being increasingly reported.
A Davin-Regli +76 more
core +2 more sources
Imipenem Induced Transcriptional Modulation of Multidrug Efflux Pumps and Porin Genes in Carbapenem Resistant Escherichia coli Isolates of Animal Origin [PDF]
, 2022 U. Jaiswal +5 more
openalex +1 more source
Chromosome‐scale genome assembly of the South American fruit fly, Anastrepha fraterculus sp.1
Insect Science, EarlyView.Anastrepha fraterculus sp. 1 is a major fruit fly pest in Argentina, currently controlled through chemical treatments and traps. This study aims to enhance the genomic understanding of this species to support the development of sterile insect technique as well as the use of innovative technologies.
Máximo Rivarola +15 more
wiley +1 more source
Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms [PDF]
, 2015 Objectives: To gain a more detailed understanding of endogenous (mutational) and exogenous (horizontally acquired) resistance to silver in Gram-negative pathogens, with an emphasis on clarifying the genetic bases for resistance.
Busse, D +4 more
core +2 more sources
The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress
The FEBS Journal, EarlyView.Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna +5 more
wiley +1 more source
International Journal of Medical Microbiology, 2021 Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram +8 more
doaj +1 more source
Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis [PDF]
, 2016 More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their ...
Philips, Jennifer A +5 more
core +2 more sources