Results 141 to 150 of about 445,929 (364)
A proposed modification of the dinamic subgrid scale closure method [PDF]
arXiv, 2011 A proposed modification of the dinamic subgrid scale closure method for LES.
arxiv
Archaeal S-layer glycoproteins: post-translational modification in the face of extremes [PDF]
, 2014 Corresponding to the sole or basic component of the surface (S)-layer surrounding the archaeal cell in most known cases, S-layer glycoproteins are in direct contact with the harsh environments that characterize niches where Archaea can thrive ...
Jerry Eichler, Lina Kandiba
core +2 more sources
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Diverse regulatory manners of human telomerase reverse transcriptase
Cell Communication and Signaling, 2019 Human telomerase reverse transcriptase (hTERT) is the core subunit of human telomerase and plays important roles in human cancers. Aberrant expression of hTERT is closely associated with tumorigenesis, cancer cell stemness maintaining, cell proliferation,
Meng-Meng Jie +9 more
doaj +1 more source
Robustness and parameter geography in post-translational modification systems.
PLoS Computational Biology, 2020 Biological systems are acknowledged to be robust to perturbations but a rigorous understanding of this has been elusive. In a mathematical model, perturbations often exert their effect through parameters, so sizes and shapes of parametric regions offer ...
Kee-Myoung Nam +4 more
doaj +1 more source
A Review of Proximity Effect Correction in Electron-beam Lithography [PDF]
arXiv, 2015 I review the work of proximity effect correction (PEC) in electron-beam (e-beam) lithography with emphasis on dose modification and shape modification PEC techniques.
arxiv
Lysine post-translational modifications of collagen
Essays in Biochemistry, 2012 Type I collagen is the most abundant structural protein in vertebrates. It is a heterotrimeric molecule composed of two α1 chains and one α2 chain, forming a long uninterrupted triple helical structure with short non-triple helical telopeptides at both the N- and C-termini.
Mitsuo Yamauchi, Marnisa Sricholpech
openaire +3 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
The Human Thioredoxin System: Modifications and Clinical Applications [PDF]
Iranian Journal of Basic Medical Sciences, 2011 The thioredoxin system, comprising thioredoxin (Trx), thioredoxin reductase (TrxR) and NADPH, is one of the major cellular antioxidant systems, implicated in a large and growing number of biological functions.
Seyed Isaac Hashemy
doaj
Orthopaedic Surgery, 2019 Objective For the purpose of providing evidence for the treatment of osteoporosis and osteopenia, this study retrospectively identified succinylation‐modified sites and proteins in postmenopausal women, and bioinformatics analysis were performed. Methods
Li‐li Zhang +6 more
doaj +1 more source