Results 11 to 20 of about 408,148 (234)
Phosphorylation of Kindlins and the Control of Integrin Function
Cells, 2021 Integrins serve as conduits for the transmission of information between cells and their extracellular environment. Signaling across integrins is bidirectional, transducing both inside-out and outside-signaling.
Katarzyna Bialkowska +2 more
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Post-Translational Modifications of Extracellular Proteasome
Molecules, 2020 The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways in eukaryotic cells. Abnormal functioning of this system has been observed in cancer and neurological diseases.
Anna S. Tsimokha +4 more
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Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]
, 2012 Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone +2 more
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Post-translational Modifications of the Protein Termini
Frontiers in Cell and Developmental Biology, 2021 Post-translational modifications (PTM) involve enzyme-mediated covalent addition of functional groups to proteins during or after synthesis. These modifications greatly increase biological complexity and are responsible for orders of magnitude change ...
Li Chen, Anna Kashina
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Protein modification and maintenance systems as biomarkers of ageing [PDF]
, 2015 Changes in the abundance and post-translational modification of proteins and accumulation of some covalently modified proteins have been proposed to represent hallmarks of biological ageing.
Friguet, Bertrand +7 more
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Post-Translational Modifications Control Phase Transitions of Tau [PDF]
ACS Central ScienceWyatt C. Powell +10 more
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An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]
, 2015 Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro +1 more
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Post-translational modifications in neurodegeneration
AIMS Biophysics, 2015 Post-translational modifications increase proteome functionality for managing all aspects of normal cell biology. They are based on the covalent attachment of functional groups, leading to phosphorylation, acetylation, glycosylation, acylation ...
Federico Benetti, Alessandro Didonna
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Post-Translational Modifications of TRP Channels
Cells, 2014 Transient receptor potential (TRP) channels constitute an ancient family of cation channels that have been found in many eukaryotic organisms from yeast to human.
Olaf Voolstra, Armin Huber
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System level dynamics of post-translational modifications [PDF]
, 2014 Attempts to characterize cellular behaviors with static, univariate measurements cannot fully capture biological complexity and lead to an inadequate interpretation of cellular processes.
Gajadhar, Aaron, White, Forest M.
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