Results 251 to 260 of about 541,798 (360)

Targeting epigenetic and post-translational modifications of NRF2: key regulatory factors in disease treatment. [PDF]

Cell Death Discov
Yang X, Liu Y, Cao J, Wu C, Tang L, Bian W, Chen Y, Yu L, Wu Y, Li S, Shen Y, Xia J, Du J.   +12 more
europepmc   +1 more source

Structural determinants of post-translational modification and catalytic specificity for the lipoyl domains of the pyruvate dehydrogenase multienzyme complex of Escherichia coli

, 2000
D. Dafydd Jones, H.James Horne, Pedro A. Reche, Richard N. Perham   +3 more
openalex   +2 more sources

Global Regulation of Post-translational Modifications on Core Histones [PDF]

, 2002
Scott Galasinski, Donna F. Louie, Kristen K. Gloor, Katheryn A. Resing, Natalie G. Ahn   +4 more
openalex   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

Post-translational modifications in hepatocellular carcinoma: unlocking new frontiers in immunotherapy. [PDF]

Front Immunol
Piao Y, Zhai N, Zhang X, Zhao W, Li M.
europepmc   +1 more source

Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis [PDF]

, 2003
Jacintha O’Sullivan, Lorna Whyte, Jim Drake, Martin Tenniswood   +3 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

PTMVision: An Interactive Visualization Webserver for Post-translational Modifications of Proteins. [PDF]

J Proteome Res
Hackl S, Jachmann C, Witte Paz M, Harbig TA, Martens L, Nieselt K.   +5 more
europepmc   +1 more source

Post-translational Modification of Bid Has Differential Effects on Its Susceptibility to Cleavage by Caspase 8 or Caspase 3 [PDF]

, 2003
Mauro Degli Esposti, Gilles Ferry, Peggy Masdehors, Jean A. Boutin, John A. Hickman, Caroline Dive   +5 more
openalex   +1 more source

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal‐Phenolic Networks

Advanced Healthcare Materials, EarlyView.
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima   +8 more
wiley   +1 more source