Results 301 to 310 of about 450,881 (322)
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RIP1 post-translational modifications
Biochemical Journal, 2022Receptor interacting protein 1 (RIP1) kinase is a critical regulator of inflammation and cell death signaling, and plays a crucial role in maintaining immune responses and proper tissue homeostasis. Mounting evidence argues for the importance of RIP1 post-translational modifications in control of its function.
Eugene Varfolomeev, Domagoj Vucic
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Post-translational modifications of lantibiotics
Antonie van Leeuwenhoek, 1996Several newly reported post-translational modification reactions are involved in lantibiotic biosynthesis. A short overview of the present knowledge on the post-translational modifications and on the enzymes involved in lantibiotic biosynthesis is given. The oxidative decarboxylation of the epidermin precursor peptide EpiA is described in detail.
Friedrich Götz, Thomas Kupke
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The evolution of post-translational modifications
Current Opinion in Genetics & Development, 2022Post-translational modifications (PTMs) are chemical modifications that can regulate the activity and function of proteins. From an evolutionary perspective, they also represent a fast mechanism for the generation of phenotypic diversity and divergence.
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Post-translational Modification
2016Posttranslational modifications, including chemical and covalent conjugation of small proteins, play dynamic regulatory roles underlying the functional modulation of proteins. Posttranslational modifications mediate virtually all cellular processes including cell proliferation, differentiation, apoptosis, and epigenetics in both physiological and ...
Jun Wang +2 more
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Proteomic analysis of post-translational modifications
Nature Biotechnology, 2003Post-translational modifications modulate the activity of most eukaryote proteins. Analysis of these modifications presents formidable challenges but their determination generates indispensable insight into biological function. Strategies developed to characterize individual proteins are now systematically applied to protein populations.
Mann, Matthias, Jensen, Ole N
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Post-translational Modifications of Centromeric Chromatin
2017Regulation of chromatin structures is important for the control of DNA processes such as gene expression, and misregulation of chromatin is implicated in diverse diseases. Covalent post-translational modifications of histones are a prominent way to regulate chromatin structure and different chromatin regions bear their specific signature of histone ...
García del Arco, Ana, Erhardt, Sylvia
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