Results 31 to 40 of about 541,798 (360)
Regulation of DELLA Proteins by Post-translational Modifications [PDF]
Plant and Cell Physiology, 2020 DELLA proteins are the negative regulators of the gibberellin (GA) signaling pathway. GAs have a pervasive effect on plant physiology, influencing processes that span the entire life cycle of the plant.
Noel Blanco-Touri��n +2 more
semanticscholar +6 more sources
Post-translational modifications in liver disease [PDF]
, 2017 154 p.La enfermedad hepática crónica es un término que incluye una larga lista de patologías hepáticas y que suele finalizar con la pérdida de integridad del parénquima hepático degenerando en cirrosis y carcinoma hepatocelular (CHC).
Zubiete Franco, Imanol
core +4 more sources
MedComm, 2023 Histones are DNA‐binding basic proteins found in chromosomes. After the histone translation, its amino tail undergoes various modifications, such as methylation, acetylation, phosphorylation, ubiquitination, malonylation, propionylation, butyrylation ...
Ruiqi Liu +9 more
semanticscholar +1 more source
Signal Transduction and Targeted Therapy, 2023 Autophagy is a conserved lysosomal degradation pathway where cellular components are dynamically degraded and re-processed to maintain physical homeostasis. However, the physiological effect of autophagy appears to be multifaced.
F. Shu +8 more
semanticscholar +1 more source
Enzyme-less nanopore detection of post-translational modifications within long polypeptides
bioRxiv, 2023 Means to sequence DNA and RNA quickly and cheaply have revolutionized biology and medicine. The ability to analyse cellular proteins and their millions of variants would be an advance of comparable importance, but requires a fresh technical approach.
Pablo Martin-Baniandres +6 more
semanticscholar +1 more source
Post-translation modifications [PDF]
Current Opinion in Chemical Biology, 2009 The development of proteomics has been one of the great achievements in analytical chemical biology in the past ten years. The determination of the total protein constituents in biological samples has allowed new and unprecedented insights into cellular processes and diseases.
Lara K. Mahal, Carlito B. Lebrilla
openaire +3 more sources
Post translational modification of Parkin [PDF]
Biology Direct, 2017 Mutations in the gene encoding for the E3 ubiquitin ligase Parkin are associated to a rare form of familiar autosomal recessive Parkinsonism. Despite decades of research on the Parkin protein, whose structure has been recently solved, little is known about the specific signalling pathways that lead to Parkin activation.
Chakraborty, Joy +2 more
openaire +4 more sources
Post-translational modifications of microtubules [PDF]
Journal of Cell Science, 2010 Microtubules – polymers of tubulin – perform essential functions, including regulation of cell shape, intracellular transport and cell motility. How microtubules are adapted to perform multiple diverse functions is not well understood. Post-translational modifications of tubulin subunits diversify the outer and luminal surfaces of microtubules and ...
Dorota Wloga, Jacek Gaertig
openaire +5 more sources
Post-translational modifications in liquid-liquid phase separation: a comprehensive review
Molecular Biomedicine, 2022 Liquid-liquid phase separation (LLPS) has received significant attention in recent biological studies. It refers to a phenomenon that biomolecule exceeds the solubility, condensates and separates itself from solution in liquid like droplets formation ...
Jingxian Li +6 more
semanticscholar +1 more source
Post-translational modifications of tubulin [PDF]
Current Biology, 2014 Microtubules are the largest filamentous components of the eukaryotic cytoskeleton. In spite of their extraordinary level of structural conservation, microtubules fulfill a vast range of different functions in cells. How this functional diversity is achieved remains an open question; however, recent advances point towards post-translational ...
Carsten Janke, Maria M. Magiera
openaire +3 more sources