Results 31 to 40 of about 447,325 (322)
An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]
, 2015 Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro +1 more
core +1 more source
The next frontier of post‐translational modifications [PDF]
, 2013 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/101883/1/bip22370 ...
Martin, Brent R.
core +1 more source
Protein modification and maintenance systems as biomarkers of ageing [PDF]
, 2015 Changes in the abundance and post-translational modification of proteins and accumulation of some covalently modified proteins have been proposed to represent hallmarks of biological ageing.
Friguet, Bertrand +7 more
core +3 more sources
Mycobacterium tuberculosis H37Ra: a surrogate for the expression of conserved, multimeric proteins of M.tb H37Rv [PDF]
, 2016 Additional file 3. Details of primers used, experimental and theoretical molecular weights, pI values and details of post-translational modifications in ...
Ajay Kumar +13 more
core +5 more sources
Post‐translation modification of proteins in tears [PDF]
ELECTROPHORESIS, 2010 AbstractThis is the first 2‐DE study using sequential dyes to analyse phospho‐, glyco‐ and total tear protein profiles (Pro‐Q Diamond for phosphoprotein, Pro‐Q Emerald for glycoprotein and Sypro Ruby for total protein). This method minimised the gel–gel variations, allowing better comparisons among the three profiles and generated a whole map of PTM ...
Yong Li +14 more
openaire +3 more sources
Post-translational protein modifications in schizophrenia [PDF]
npj Schizophrenia, 2020 AbstractResearch investigating the pathophysiology of schizophrenia has not yet precisely defined the molecular phenotype of this disorder. Many studies have investigated cellular dysfunction by examining expression levels of molecular targets in postmortem patient brain; however, inconsistencies between transcript and protein measures in schizophrenia
Toni M. Mueller +1 more
openaire +2 more sources
Oxidatively Modified Proteins: Cause and Control of Diseases
Applied Sciences, 2020 Proteins succumb to numerous post-translational modifications (PTMs). These relate to enzymatic or non-enzymatic reactions taking place in either the intracellular or extracellular compartment.
Ramona Clemen, Sander Bekeschus
doaj +1 more source
SLoMo: automated site localization of modifications from ETD/ECD mass spectra [PDF]
, 2009 Recently, software has become available to automate localization of phosphorylation sites from CID data and to assign associated confidence scores. We present an algorithm, SLoMo (Site Localization of Modifications), which extends this capability to ETD ...
Bailey, Christopher M +5 more
core +1 more source
System level dynamics of post-translational modifications [PDF]
, 2014 Attempts to characterize cellular behaviors with static, univariate measurements cannot fully capture biological complexity and lead to an inadequate interpretation of cellular processes.
Gajadhar, Aaron, White, Forest M.
core +1 more source
Post-translational modifications of transporters
Pharmacology & Therapeutics, 2018 Drug transporter proteins are critical to the distribution of a wide range of endogenous compounds and xenobiotics such as hormones, bile acids, peptides, lipids, sugars, and drugs. There are two classes of drug transporters- the solute carrier (SLC) transporters and ATP-binding cassette (ABC) transporters -which predominantly differ in the energy ...
Lindsay C. Czuba +2 more
openaire +4 more sources