Results 231 to 240 of about 85,477 (330)

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Post-translational modifications in osteogenic differentiation of oral-derived stem cells: Mechanisms and clinical implications. [PDF]

World J Stem Cells
Shi ZJ, Liu W.
europepmc   +1 more source

Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates

PROTEOMICS, EarlyView.
ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre, Jens Hamar, Monica B. Urias, Dietmar Kültz   +3 more
wiley   +1 more source

Post-translational modifications in heat stress-related diseases. [PDF]

Front Mol Biosci
Cui Q, Jia K, Li F, Zheng J, Wang F.
europepmc   +1 more source

Quantitative Top–Down Proteomics Reveals Significant Differences in Histone Proteoforms Between Metastatic and Nonmetastatic Colorectal Cancer Cells

PROTEOMICS, EarlyView.
ABSTRACT Colorectal cancer (CRC) development is closely associated with the accumulation of both genetic and epigenetic alterations. Many efforts have been made to investigate the role of epigenetic modifications in CRC metastasis. In this work, we present the quantitative top‐down proteomics study focusing on histone proteoforms between metastatic ...
Fei Fang, Brian Fries, Zhige Wang, Xiaowen Liu, Amanda B. Hummon, Liangliang Sun   +5 more
wiley   +1 more source

The role of post-translational modifications in the dynamics of cytoplasmic biomolecular condensates in plants. [PDF]

New Phytol
Legoux M, Reichheld JP, Merret R.
europepmc   +1 more source

Complete data and PTMs identified in detected peptides present in the potato protein hydrolysate from Peptidomics of potato protein hydrolysates: implications of post-translational modifications in food peptide structure and behaviour

, 2018
Shixiang Yao, Chibuike C. Udenigwe
openalex   +2 more sources

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

Genetic code expansion and enzymatic modifications as accessible methods for studying site-specific post-translational modifications of alpha-synuclein and tau. [PDF]

Protein Sci
Saleh IG, Shimogawa M, Ramirez J, Abakah B, Venkatesh Y, James HP, Li MH, Louie SA, Lougee MG, Chia WK, Brue C, Cooley RB, Mehl RA, Baumgart T, Mach RH, Eliezer D, Rhoades E, Petersson EJ.   +17 more
europepmc   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source