Results 71 to 80 of about 85,477 (330)

Estrogen Receptor Alpha Splice Variants, Post-Translational Modifications, and Their Physiological Functions

open access: yesCells, 2023
The importance of estrogenic signaling for a broad spectrum of biological processes, including reproduction, cancer development, energy metabolism, memory and learning, and so on, has been well documented.
Kenji Saito, H. Cui
semanticscholar   +1 more source

Evolution and functional cross‐talk of protein post‐translational modifications

open access: yesMolecular Systems Biology, 2013
Protein post‐translational modifications (PTMs) allow the cell to regulate protein activity and play a crucial role in the response to changes in external conditions or internal states.
Pedro Beltrao   +3 more
doaj   +1 more source

Protein post-translational modifications: In silico prediction tools and molecular modeling

open access: yesComputational and Structural Biotechnology Journal, 2017
Post-translational modifications (PTMs) occur in almost all proteins and play an important role in numerous biological processes by significantly affecting proteins' structure and dynamics.
Martina Audagnotto, Matteo Dal Peraro
doaj   +1 more source

Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]

open access: yes, 2015
Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar   +3 more
core   +3 more sources

Diagnostic and Prognostic Value of Protein Post-translational Modifications in Hepatocellular Carcinoma

open access: yesJournal of Clinical and Translational Hepatology, 2023
Hepatocellular carcinoma (HCC) is a common malignant tumor with high incidence and cancer mortality worldwide. Post-translational modifications (PTMs) of proteins have a great impact on protein function.
Jing Wang   +5 more
semanticscholar   +1 more source

Perspectives on pediatric congenital aortic valve stenosis: Extracellular matrix proteins, post translational modifications, and proteomic strategies

open access: yesFrontiers in Cardiovascular Medicine, 2022
In heart valve biology, organization of the extracellular matrix structure is directly correlated to valve function. This is especially true in cases of pediatric congenital aortic valve stenosis (pCAVS), in which extracellular matrix (ECM) dysregulation
Cassandra L. Clift   +4 more
doaj   +1 more source

Post-translational modifications and immune responses in liver cancer

open access: yesFrontiers in Immunology, 2023
Post-translational modification (PTM) refers to the covalent attachment of functional groups to protein substrates, resulting in structural and functional changes.
You-Wei Wang   +3 more
semanticscholar   +1 more source

Regulation of insulin secretion by the post-translational modifications

open access: yesFrontiers in Cell and Developmental Biology, 2023
Post-translational modification (PTM) has a significant impact on cellular signaling and function regulation. In pancreatic β cells, PTMs are involved in insulin secretion, cell development, and viability.
Chunhua Yang   +7 more
semanticscholar   +1 more source

Post-translational modifications in liquid-liquid phase separation: a comprehensive review

open access: yesMolecular Biomedicine, 2022
Liquid-liquid phase separation (LLPS) has received significant attention in recent biological studies. It refers to a phenomenon that biomolecule exceeds the solubility, condensates and separates itself from solution in liquid like droplets formation ...
Jingxian Li   +6 more
semanticscholar   +1 more source

Bioprocess Development for Lantibiotic Ruminococcin-A Production in Escherichia coli and Kinetic Insights Into LanM Enzymes Catalysis [PDF]

open access: yes, 2019
Ruminococcin-A (RumA) is a peptide antibiotic with post-translational modifications including thioether cross-links formed from non-canonical amino acids, called lanthionines, synthesized by a dedicated lanthionine-generating enzyme RumM.
Adrian, Lorenz   +5 more
core   +1 more source

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