Results 71 to 80 of about 81,942 (295)
Identification of ultramodified proteins using top-down tandem mass spectra [PDF]
Post-translational modifications (PTMs) play an important role in various biological processes through changing protein structure and function.
Hengel, Shawna+5 more
core +1 more source
Evolution and functional cross‐talk of protein post‐translational modifications
Protein post‐translational modifications (PTMs) allow the cell to regulate protein activity and play a crucial role in the response to changes in external conditions or internal states.
Pedro Beltrao+3 more
doaj +1 more source
Throughout various stages of its life cycle, influenza A virus relies heavily on host cellular machinery, including the post-translational modifications (PTMs) system.
Jiao Hu+8 more
doaj +1 more source
Post-translational modifications in proteins: resources, tools and prediction methods
Posttranslational modifications (PTMs) refer to amino acid side chain modification in some proteins after their biosynthesis. There are more than 400 different types of PTMs affecting many aspects of protein functions.
Shahin Ramazi, J. Zahiri
semanticscholar +1 more source
Role of non-canonical post-translational modifications in gastrointestinal tumors
Post-translational modifications (PTMs) of proteins contribute to the occurrence and development of tumors. Previous studies have suggested that canonical PTMs such as ubiquitination, glycosylation, and phosphorylation are closely implicated in different
Yihong Liu+6 more
doaj +1 more source
PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data [PDF]
Interactions among transcriptional factors (TFs), cofactors and other proteins or enzymes can affect transcriptional regulatory capabilities of eukaryotic organisms. Post-translational modifications (PTMs) cooperate with TFs and epigenetic alterations to
Boheler, KR+8 more
core +1 more source
Recent advances in malaria genomics and epigenomics [PDF]
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian+2 more
core +1 more source
Identifying Protein Interactions with Histone Peptides Using Bio-layer Interferometry
Histone post-translational modifications (PTMs) regulate numerous cellular processes, including gene transcription, cell division, and DNA damage repair. Most histone PTMs affect the recruitment or exclusion of reader proteins from chromatin.
Bingbing Ren+4 more
doaj +1 more source
Many biopharmaceuticals exhibit mixed heterogeneity in their post-translational modifications (PTMs) that are essential for their function. Here the authors use a combination of mass spectrometry techniques to analyse human erythropoietin (EPO) and ...
Yang Yang+5 more
doaj +1 more source
Aldehyde dehydrogenase 2 (ALDH2) has both dehydrogenase and esterase activity; its dehydrogenase activity is closely related to the metabolism of aldehydes produced under oxidative stress (OS). In this review, we recapitulate the enzyme activity of ALDH2
Jie Gao, Y. Hao, X. Piao, X. Gu
semanticscholar +1 more source