Results 161 to 170 of about 14,425,416 (299)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Post-Treatment Persistent Erythrocytosis in Patients with Hodgkin Lymphoma: Molecular Mechanisms Underlying the Pathogenesis of Erythrocytosis. [PDF]

Cancers (Basel)
Koyun D, Yüksel S, Civriz Bozdağ S, Tuncalı T, Kuzu I, Özcan M.   +5 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Other title: Assessing the Department of Social and Rehabilitation Services' contracted managed-care program for substance abuse treatment and prevention

, 1998
Cover title.; "A report to the Legislative Post Audit Committee."; "August 1998 ...

core  

TB preventive treatment coverage among children under six years of age in TB-affected households

IJTLD Open
A. Kadam, A.H. Moe, M.S. Barthwal, G. Lele, A. Kakrani, V. Mave, N. Suryavanshi, J.E. Golub, S.R. Cox, on behelf of the TB Aftermath study team, A. Mahajan, Y. Bhosale, S. Dugga, P. Kadam, S. Jadhav, V. Bodhe, P. Bhalchim, S. Rathod, V. Dhamale, N. Sonawane, P. Ambekar, A. Bhalchim, A. Patole   +22 more
doaj   +1 more source

Constitutive natural killer cell features associated with post-treatment control of SIV infection in the pVISCONTI study. [PDF]

Nat Commun
Chapel A, Romero-Martín L, Passaes C, Monceaux V, Volant S, Desjardins D, Melard A, David A, Dereuddre-Bosquet N, Rouzioux C, Avettand-Fenoel V, Müller-Trutwin M, Le Grand R, Sáez-Cirión A.   +13 more
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

L-DOPA Promotes Post-Treatment Neurovascular and Synaptic Homeostasis in Early Diabetic Retinopathy. [PDF]

Invest Ophthalmol Vis Sci
Chlan E, Li C, Bales KL, Wood LB, Pardue MT.   +4 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Ventilatory Efficiency During Exercise in CTEPH and PAH Pre- and Post-Treatment. [PDF]

Pulm Circ
Schwarz EI, Benning L, Bousraou Z, Müller J, Lichtblau M, Opitz I, Ulrich S.   +6 more
europepmc   +1 more source