Results 161 to 170 of about 10,517,225 (330)

Buried Treasure? Overlooked and Newly Discovered Evolutionary Contributions to Human Brain Diseases

open access: yesAnnals of Neurology, EarlyView.
Recapitulative schema of different exploratory levels of the evolutionary impact on human neurological diseases. Clinical neuroscience focuses on the mechanisms of brain function, but this approach falls short of insights into how the central nervous system (CNS) evolved, both in health and disease.
Nico J. Diederich   +20 more
wiley   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

open access: yesAnnals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Pre- and Post-synaptic Mechanisms of Neuronal Inhibition Assessed Through Biochemically Detailed Modeling of GABA<sub>B</sub> Receptor Signaling. [PDF]

open access: yesJ Neurosci
Mäki-Marttunen T   +8 more
europepmc   +1 more source

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

open access: yesAdvanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang   +7 more
wiley   +1 more source

Optoelectronic Mesoporous Titania Memristor with Light‐Modulation by Laser Pointer

open access: yesAdvanced Physics Research, EarlyView.
Optoelectronic synaptic device based on thin film mesoporous titania is demonstrated as visual sensing layer under illumination of low power laser pointers, which could modulate weight change of input signal. Through both photonic and electronic co‐modulation on the Al/meso‐TiO2/ITO device array, multiple hand writings “3” and “5” by laser pointer ...
Dhanashri Vittahl Desai   +3 more
wiley   +1 more source

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