Results 11 to 20 of about 134,202 (290)

Transcranial focused ultrasound induces sustained synaptic plasticity in rat hippocampus

open access: yesBrain Stimulation, 2022
Transcranial focused ultrasound (tFUS) neuromodulation provides a promising emerging non-invasive therapy for the treatment of neurological disorders.
Xiaodan Niu, Kai Yu, Bin He
doaj   +1 more source

AMPA Receptor Trafficking for Postsynaptic Potentiation [PDF]

open access: yesFrontiers in Cellular Neuroscience, 2018
Long-term potentiation (LTP) of excitatory synaptic strength, which has long been considered a synaptic correlate for learning and memory, requires a fast recruitment of additional α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors (AMPARs) to the postsynaptic sites.
Mikyoung Park, Mikyoung Park
openaire   +3 more sources

Functional maps of neocortical local circuitry

open access: yesFrontiers in Neuroscience, 2007
This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
doaj   +1 more source

Influence of Mpv17 on Hair-Cell Mitochondrial Homeostasis, Synapse Integrity, and Vulnerability to Damage in the Zebrafish Lateral Line

open access: yesFrontiers in Cellular Neuroscience, 2021
Noise exposure is particularly stressful to hair-cell mitochondria, which must produce enough energy to meet high metabolic demands as well as regulate local intracellular Ca2+ concentrations.
Melanie Holmgren   +2 more
doaj   +1 more source

Modeling Calcium Dynamics and Inhibition Based Synaptic Plasticity in Dendritic Spines

open access: yesMathematical Modelling and Analysis, 2014
Inhibitory synapses through GABAergic channels not only change spine's calcium dynamics but also modulate postsynaptic current mediated through glutamate receptors.
Muhammad Dur-e-Ahmad
doaj   +1 more source

Brain Dystrophin in Duchenne Dystrophy

open access: yesPediatric Neurology Briefs, 1995
To define the potential pathogenic role of dystrophin deficiency in the cognitive impairment characteristic of Duchenne muscular dystrophy (DMD), the protein in brain cortical synapses of an 8-year-old patient examined at autopsy and an age-matched ...
J Gordon Millichap
doaj   +1 more source

Retrograde Synaptic Signaling Mediated by K+ Efflux through Postsynaptic NMDA Receptors

open access: yesCell Reports, 2013
Synaptic NMDA receptors (NMDARs) carry inward Ca2+ current responsible for postsynaptic signaling and plasticity in dendritic spines. Whether the concurrent K+ efflux through the same receptors into the synaptic cleft has a physiological role is not ...
Pei-Yu Shih   +7 more
doaj   +1 more source

Impairment Mechanisms and Intervention Approaches for Aged Human Neuromuscular Junctions

open access: yesFrontiers in Molecular Neuroscience, 2020
The neuromuscular junction (NMJ) is a chemical synapse formed between a presynaptic motor neuron and a postsynaptic muscle cell. NMJs in most vertebrate species share many essential features; however, some differences distinguish human NMJs from others ...
Yomna Badawi   +2 more
doaj   +1 more source

Occurrence of Ordered and Disordered Structural Elements in Postsynaptic Proteins Supports Optimization for Interaction Diversity

open access: yesEntropy, 2019
The human postsynaptic density is an elaborate network comprising thousands of proteins, playing a vital role in the molecular events of learning and the formation of memory.
Annamária Kiss-Tóth   +6 more
doaj   +1 more source

GABAergic synaptic transmission regulates calcium influx during spike-timing dependent plasticity

open access: yesFrontiers in Synaptic Neuroscience, 2010
Coincident pre- and postsynaptic activity of hippocampal neurons alters the strength of gamma-aminobutyric acid (GABAA)-mediated inhibition through a Ca2+-dependent regulation of cation-chloride cotransporters.
Trevor Balena   +2 more
doaj   +1 more source

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